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Effects of Music During Walking on Pain and Muscle Activation in People With Chronic Pain Due to Knee Osteoarthritis

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Summary

NIH registered a new clinical trial on ClinicalTrials.gov (NCT07537114) to study the effects of rhythmic auditory stimulation—walking with music versus walking with a metronome versus walking without sound—on pain and muscle activation in individuals with chronic knee osteoarthritis. The trial will enroll participants receiving one of three interventions: rhythmic auditory stimulation with music, rhythmic auditory stimulation with a metronome, or a control group with no auditory cueing.

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What changed

NIH has registered a new clinical trial (NCT07537114) on ClinicalTrials.gov titled 'Effects of Music During Walking on Pain and Muscle Activation in People With Chronic Pain Due to Knee Osteoarthritis.' The trial will study three walking interventions: rhythmic auditory stimulation with music, rhythmic auditory stimulation with a metronome, and a control condition with no auditory cueing. Participants diagnosed with knee osteoarthritis will be enrolled and assessed for changes in pain sensitivity, muscle activation, and brain function.

Healthcare providers and clinical investigators involved in musculoskeletal or pain research may find this trial relevant to ongoing studies in osteoarthritis management. The trial does not create compliance obligations for regulated entities; it is an informational registration entry in the ClinicalTrials.gov registry. Parties interested in the study outcomes or potential collaboration should contact the sponsoring institution directly.

Archived snapshot

Apr 18, 2026

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Effects of Music During Walking on Pain and Muscle Activation in People With Chronic Pain Due to Knee Osteoarthritis

N/A NCT07537114 Kind: NA Apr 17, 2026

Abstract

The purpose of this research study is to compare muscle activation, changes in pain sensitivity, and brain function, between different walking conditions, including walking to music, walking to metronome, and walking without music or metronome.

Conditions: Knee Osteoarthritis

Interventions: Rhythmic Auditory Stimulation with music, Rhythmic Auditory Stimulation with metronome, Control

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Last updated

Classification

Agency
NIH
Published
April 17th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
NCT07537114
Docket
NCT07537114

Who this affects

Applies to
Healthcare providers Patients
Industry sector
6211 Healthcare Providers
Activity scope
Clinical trial registration Pain management research
Geographic scope
United States US

Taxonomy

Primary area
Healthcare
Operational domain
Clinical Operations
Compliance frameworks
GxP
Topics
Public Health Medical Devices

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