Multicenter RCT: Laparoscopic Staging for Stage III Gastric Cancer

NIH has added a new clinical trial registration (NCT07533825) to ClinicalTrials.gov for a multicenter randomized controlled trial studying laparoscopic staging-guided precision treatment for stage III gastric cancer. The trial will enroll patients with clinical stage III gastric cancer or gastric adenocarcinoma and randomly assign them to receive either laparoscopic staging-guided therapy or treatment without laparoscopic exploration.

Affected parties include healthcare providers conducting cancer research, clinical investigators at participating study sites, and patients seeking enrollment in gastric cancer clinical trials. The trial aims to establish evidence for precision staging and treatment decision-making in stage III gastric cancer, with results potentially influencing future clinical practice guidelines for gastric cancer staging.