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Comparing Medial and Lateral Dissection Approaches to the Recurrent Laryngeal Nerve During a Thyroidectomy

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Summary

NIH registered a new interventional clinical trial (NCT07532889) comparing medial versus lateral dissection approaches to the recurrent laryngeal nerve during thyroidectomy. The randomized study will evaluate length of hospital stay, surgical adverse events, and post-operative vocal cord function. Participants scheduled for thyroidectomy will be enrolled after informed consent.

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What changed

NIH registered a new randomized interventional study comparing two surgical approaches to identifying the recurrent laryngeal nerve during thyroidectomy. The trial will assign participants to either the new medial approach or the standard lateral approach and measure outcomes including hospital stay duration, intraoperative adverse events, and post-operative vocal cord function.

For healthcare providers and clinical investigators, this registry entry indicates a new comparative effectiveness research opportunity in thyroid surgery. The study does not impose regulatory obligations but reflects ongoing surgical technique research that may inform future clinical practice guidelines.

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Archived snapshot

Apr 16, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

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Comparing Medial and Lateral Dissection Approaches to the Recurrent Laryngeal Nerve During a Thyroidectomy

N/A NCT07532889 Kind: NA Apr 16, 2026

Abstract

The goal of this interventional study is to compare the effectiveness of two surgical approaches in identifying the recurrent laryngeal nerve (RLN) during thyroidectomy. The main questions it aims to answer are:

How does each approach affect the length of hospital stay? How does each approach affect the number of adverse events that occur during surgery? How does each approach affect vocal cord function after surgery?

Researchers will compare the new medial approach to the standard lateral approach to evaluate its effectiveness.

Participants scheduled to undergo thyroidectomy surgery will be randomly assigned to one of these approaches after informed consent is obtained. Data will be collected during and after the surgery by a research assistant.

Conditions: Thyroidectomy

Interventions: Approach to RLN during Thyroidectomy

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Last updated

Classification

Agency
NIH
Published
April 16th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
NCT07532889

Who this affects

Applies to
Healthcare providers Clinical investigators
Industry sector
6221 Hospitals & Health Systems
Activity scope
Clinical trial registration Surgical procedure research Patient outcome studies
Geographic scope
United States US

Taxonomy

Primary area
Healthcare
Operational domain
Clinical Operations
Topics
Medical Devices Public Health

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