Effects of 7-Day Creatine Supplementation on Cognitive Function After High-Intensity Interval Training in Active Young Men
Summary
NIH ClinicalTrials.gov registered a new clinical trial (NCT07534293) to evaluate whether 7-day creatine monohydrate supplementation affects cognitive function after high-intensity interval training in active young men. The randomized controlled trial will enroll 20 participants across four groups receiving placebo or creatine at 0.1 or 0.3 g/KgBW/day, with or without exercise, measuring outcomes via visual reaction time and Trail Making Tests. The trial is listed as Not Yet Recruiting with an anticipated completion date of April 16, 2026.
What changed
A new clinical trial registration was published on ClinicalTrials.gov for a study evaluating creatine monohydrate supplementation combined with high-intensity interval training on cognitive outcomes in young men. The trial protocol specifies four treatment arms: placebo with exercise, placebo without exercise, creatine 0.1 g/KgBW/day with exercise, and creatine 0.3 g/KgBW/day with exercise. Participants will undergo cognitive testing including visual reaction time, go/no-go visual reaction time, and Trail Making Tests A and B at baseline and post-intervention.
This registry entry represents an informational publication documenting a planned federally-required clinical trial registration under FDAAA 801. Clinical investigators and sponsors subject to clinical trial registration requirements should note this study for awareness of ongoing research in this therapeutic area. The trial does not create new compliance obligations for third parties.
Archived snapshot
Apr 17, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Effects of 7-Day Creatine Supplementation on Cognitive Function After High-Intensity Interval Training in Active Young Men
N/A NCT07534293 Kind: NA Apr 16, 2026
Abstract
This study evaluates whether 7-day creatine monohydrate supplementation affects cognitive function after high-intensity interval training (HIIT) in active young men. Twenty participants were assigned to one of four groups: placebo plus exercise, placebo without exercise, creatine 0.1 g/KgBW/day plus exercise, or creatine 0.3 g/KgBW/day plus exercise. Cognitive performance was measured before and after the intervention using visual reaction time, go/no-go visual reaction time, and Trail Making Tests A and B.
Conditions: Creatine Supplementation, Exercise Ergogenics
Interventions: Creatine Monohydrate, Creatine Monohydrate, Placebo, High Intensity Interval Training
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