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Compositions and Methods for Identification of VHH Antibodies That Bind a Target Antigen

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Summary

The USPTO published patent application US20260098255A1 for Broad Institute's VHH antibody identification methods. The application covers compositions and methods for identifying VHH antibodies that bind target antigens. The application (No. 19415305) was filed December 10, 2025, and published April 9, 2026.

What changed

The USPTO published Broad Institute's patent application covering compositions and methods for identifying VHH antibodies that bind target antigens. The published application (US20260098255A1) includes CPC classifications related to cellular and molecular biology methods, antibody structures, and enzymatic processes.

For biotechnology and pharmaceutical companies developing antibody therapeutics, this published application establishes a prior art date and potential freedom-to-operate considerations. Parties engaged in VHH or nanobody research should monitor this application's prosecution for claim scope and potential licensing implications.

What to do next

  1. Monitor patent prosecution status
  2. Evaluate potential licensing opportunities
  3. Review claims for freedom-to-operate analysis

Archived snapshot

Apr 11, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Applications

COMPOSITIONS AND METHODS FOR IDENTIFICATION OF VHH ANTIBODIES THAT BIND A TARGET ANTIGEN

Application US20260098255A1 Kind: A1 Apr 09, 2026

Assignee

The Broad Institute, Inc.

Inventors

Robert Manguso, Gabriel Griffin, Nelson Knudsen, Hans Pope

Abstract

Compositions and methods that are useful for identification of VHH antibodies that bind a target antigen.

CPC Classifications

C12N 15/1037 C07K 14/7051 C07K 14/70521 C12N 9/1211 C12N 15/1082 C12N 15/1086 C07K 2319/70 C12Y 207/01021

Filing Date

2025-12-10

Application No.

19415305

View original document →

Named provisions

Abstract CPC Classifications Filing Date Application No.

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Last updated

Classification

Agency
USPTO
Published
April 9th, 2026
Instrument
Rule
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
US20260098255A1
Docket
US20260098255A1

Who this affects

Applies to
Pharmaceutical companies Biotechnology companies Research institutions
Industry sector
3254.1 Biotechnology 3254 Pharmaceutical Manufacturing
Activity scope
Patent application filing Biotechnology research Antibody development
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Pharmaceuticals Biotechnology Medical Devices

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