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TNF-alpha Variant Fusion Molecules

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Summary

USPTO published patent application US20260092092A1 for TNF-alpha variant fusion molecules and their therapeutic uses. Inventors include Robin Allene Aglietti, Susannah Dale Barbee, Peter Michael Bowers, and Melanie Angelika Kleinschek. Application No. 19294212 was filed on 2025-08-07.

What changed

USPTO published patent application US20260092092A1 disclosing novel TNF-alpha variant fusion molecules and methods of using them for therapeutic applications. The application covers compositions comprising TNF-alpha variants fused to other molecules, with potential therapeutic uses in treating inflammatory and immune-related conditions. CPC classifications include C07K 14/525, A61K 38/191, and C12N 15/63.

Patent applicants and biotechnology companies should review this publication for potential prior art implications against existing or planned programs involving TNF-alpha targeted therapeutics. IP professionals should update patent landscape analyses to include this application. No compliance deadlines or penalties apply to this publication.

Archived snapshot

Apr 2, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Applications

TNF-ALPHA VARIANT FUSION MOLECULES

Application US20260092092A1 Kind: A1 Apr 02, 2026

Inventors

Robin Allene Aglietti, Susannah Dale Barbee, Peter Michael Bowers, Melanie Angelika Kleinschek

Abstract

The present disclosure relates to TNF-alpha variants and TNF-alpha variant fusion molecules and therapeutic uses of such thereof.

CPC Classifications

C07K 14/525 A61K 38/191 C12N 5/10 C12N 15/63 A61K 38/00 C07K 2319/30

Filing Date

2025-08-07

Application No.

19294212

View original document →

Named provisions

Abstract CPC Classifications

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Last updated

Classification

Agency
USPTO
Published
April 2nd, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US20260092092A1
Docket
19294212

Who this affects

Applies to
Pharmaceutical companies Drug manufacturers Healthcare providers
Industry sector
3254.1 Biotechnology 3254 Pharmaceutical Manufacturing
Activity scope
Patent Application Biopharmaceutical Research
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Pharmaceuticals Healthcare

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