Takeda's Monoclonal Antibody Inhibitor of Factor XIIa Patent Application
Summary
The USPTO has published a patent application from Takeda Pharmaceutical Company Limited for a monoclonal antibody inhibitor of Factor XIIa. The application, filed on August 12, 2025, describes methods for treating diseases associated with Factor XII, including hereditary angioedema and ocular diseases.
What changed
This document is a published patent application from Takeda Pharmaceutical Company Limited, identified as US20260085130A1, filed on August 12, 2025. The application details novel anti-Factor XIIa antibodies and their potential use in treating diseases linked to Factor XII activation, plasma prekallikrein signaling, and ocular conditions. The patent application is classified under CPC codes related to antibodies and pharmaceutical compositions.
For compliance officers in the pharmaceutical sector, this represents a new intellectual property filing that may impact future drug development and market exclusivity. While patent applications do not impose direct regulatory obligations, they signal R&D focus areas and potential future therapeutic interventions. Companies operating in related therapeutic areas should monitor the progress of this patent application and its implications for competitive landscapes and potential licensing opportunities.
Source document (simplified)
MONOCLONAL ANTIBODY INHIBITOR OF FACTOR XIIA
Application US20260085130A1 Kind: A1 Mar 26, 2026
Assignee
Takeda Pharmaceutical Company Limited
Inventors
Shauna Mason, Jon A. Kenniston, Andrew Nixon, Daniel J. Sexton, Stephen R. Comeau, Burt Adelman
Abstract
Disclosed herein are anti-Factor XIIa antibodies and methods of using such for treating diseases associated with Factor XII, including diseases associated with contact system activation, plasma prekallikrein signaling (e.g., hereditary angioedema), and ocular diseases.
CPC Classifications
C07K 16/36 A61K 2039/505 C07K 2317/21 C07K 2317/24 C07K 2317/34 C07K 2317/55 C07K 2317/76 C07K 2317/90 C07K 2317/92 C07K 2317/94
Filing Date
2025-08-12
Application No.
19297221
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