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Takeda's Monoclonal Antibody Inhibitor of Factor XIIa Patent Application

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Published August 12th, 2025
Detected March 26th, 2026
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Summary

The USPTO has published a patent application from Takeda Pharmaceutical Company Limited for a monoclonal antibody inhibitor of Factor XIIa. The application, filed on August 12, 2025, describes methods for treating diseases associated with Factor XII, including hereditary angioedema and ocular diseases.

What changed

This document is a published patent application from Takeda Pharmaceutical Company Limited, identified as US20260085130A1, filed on August 12, 2025. The application details novel anti-Factor XIIa antibodies and their potential use in treating diseases linked to Factor XII activation, plasma prekallikrein signaling, and ocular conditions. The patent application is classified under CPC codes related to antibodies and pharmaceutical compositions.

For compliance officers in the pharmaceutical sector, this represents a new intellectual property filing that may impact future drug development and market exclusivity. While patent applications do not impose direct regulatory obligations, they signal R&D focus areas and potential future therapeutic interventions. Companies operating in related therapeutic areas should monitor the progress of this patent application and its implications for competitive landscapes and potential licensing opportunities.

Source document (simplified)

← USPTO Patent Applications

MONOCLONAL ANTIBODY INHIBITOR OF FACTOR XIIA

Application US20260085130A1 Kind: A1 Mar 26, 2026

Assignee

Takeda Pharmaceutical Company Limited

Inventors

Shauna Mason, Jon A. Kenniston, Andrew Nixon, Daniel J. Sexton, Stephen R. Comeau, Burt Adelman

Abstract

Disclosed herein are anti-Factor XIIa antibodies and methods of using such for treating diseases associated with Factor XII, including diseases associated with contact system activation, plasma prekallikrein signaling (e.g., hereditary angioedema), and ocular diseases.

CPC Classifications

C07K 16/36 A61K 2039/505 C07K 2317/21 C07K 2317/24 C07K 2317/34 C07K 2317/55 C07K 2317/76 C07K 2317/90 C07K 2317/92 C07K 2317/94

Filing Date

2025-08-12

Application No.

19297221

View original document →

Named provisions

Assignee Inventors Abstract CPC Classifications Filing Date Application No.

Classification

Agency
USPTO
Published
August 12th, 2025
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US20260085130A1

Who this affects

Applies to
Drug manufacturers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Drug Development Intellectual Property
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Compliance frameworks
FDA 21 CFR Part 11 GxP
Topics
Drug Development Intellectual Property

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