Genetically modified Bacillus subtilis strain for D-psicose 3-epimerase production

USPTO issued patent grant US12595473B2 to ROQUETTE FRERES, conferring exclusive rights to a genetically modified Bacillus subtilis strain optimized for producing D-psicose 3-epimerase. The patent covers the modified bacterial strain, optimized expression vectors, and production methods using the strain.

For affected parties, this grant establishes enforceable intellectual property rights that may restrict competitors from using similar genetic engineering approaches for D-psicose production. Competitors developing alternative psicose production methods should review the patent claims to assess potential infringement risks. The assignee ROQUETTE FRERES gains exclusive commercial rights to this biotechnology for the remaining patent term.