EPO Patent: Pyrazoloquinazoline Derivatives for G12D Mutant KRAS Cancer Treatment
Summary
The European Patent Office has published patent application EP4709729A1 concerning pyrazoloquinazoline derivatives for treating G12D mutant KRAS cancer. The patent was filed by Jazz Pharmaceuticals Ireland Ltd. and lists specific inventors.
What changed
This document is a publication of a European Patent application (EP4709729A1) by Jazz Pharmaceuticals Ireland Ltd. It details pyrazoloquinazoline derivatives identified as modulators of G12D mutant KRAS, useful for the treatment of cancer. The publication includes a list of inventors and IPC classifications related to organic chemistry, medicinal preparations, and cancer treatment.
This patent publication does not impose immediate compliance obligations on regulated entities. However, it is relevant for pharmaceutical companies and drug manufacturers involved in oncology research and development, as it pertains to intellectual property in the field of cancer therapeutics. Compliance officers in the pharmaceutical sector should note this patent as it may impact future drug development strategies and competitive landscapes.
Source document (simplified)
PYRAZOLO[4,3-F]QUINAZOLINE DERIVATIVES AS MODULATORS OF G12D MUTANT KRAS USEFUL FOR THE TREATMENT OF CANCER
Publication EP4709729A1 Kind: A1 Mar 18, 2026
Applicants
Jazz Pharmaceuticals Ireland Ltd.
Inventors
JACKSON, Paula, AYLOTT, Helen Elizabeth, JONES, Clifford D, BHAMRA, Inder, RYAN, James, LENG, Daniel J, HO, Kelvin
IPC Classifications
C07D 487/04 20060101AFI20241122BHEP C07D 519/00 20060101ALI20241122BHEP A61K 31/517 20060101ALI20241122BHEP A61P 35/00 20060101ALI20241122BHEP
Designated States
AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, ME, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR
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