NIH Chemical Synthesis and Optimization Facility for Product Development
Summary
The National Institutes of Health (NIH) has announced a funding opportunity (PAR-23-193) for a Chemical Synthesis and Optimization Facility to support product development in contraception and reproductive health. The opportunity is open to various entities, including small businesses, educational institutions, and tribal governments, with a closing date of April 3, 2026.
What changed
The National Institutes of Health (NIH) has issued a funding opportunity announcement (PAR-23-193) for the establishment of a Chemical Synthesis and Optimization Facility. This facility aims to advance non-hormonal contraceptive and reproductive health product development by providing preclinical services such as high throughput screening, hit-to-lead generation, and IND/IDE-enabling studies. The opportunity is open to a wide range of applicants, including for-profit organizations (small and other than small businesses), educational institutions, various levels of government, and tribal organizations.
Eligible entities must submit applications by April 3, 2026. The NIH is seeking proposals to enable preclinical candidates for IND/IDE studies. Applicants should consult the full announcement for detailed requirements and contact grantsinfo@nih.gov for general inquiries. No cost sharing or matching is required for this grant.
What to do next
- Review Funding Opportunity Announcement PAR-23-193 for eligibility and requirements.
- Prepare and submit grant application by the closing date of April 3, 2026.
- Contact grantsinfo@nih.gov for general inquiries regarding the opportunity.
Source document (simplified)
Chemical Screening and Optimization Facility (X01 Clinical Trial Not Allowed)
Agency: National Institutes of Health
Assistance Listings: 93.865 -- Child Health and Human Development Extramural Research
Last Updated: December 3, 2024 View version history on Grants.gov
Description
The NICHD has a state-of-the-art Chemical Synthesis and Optimization Facility for advancing both non-hormonal contraceptive and reproductive health related product development. This facility has the capabilities and capacity for preclinical services including Investigational Device Exemption (IDE) or Investigational New Drug (IND)-enabling studies (e.g., protein generation, X-ray crystallography, high throughput screening, structure activity relationships, hit-to-lead generation, drug metabolism). The long-term objective is to enable a preclinical candidate for IND/IDE study(ies) that offers a safe... therapeutic option in the field of contraception, and/or reproductive health related indications (pending contractor availability and available funding). Show full description
Eligibility
Eligible applicants
Government
- City or township governments
- Special district governments
- Federally recognized Native American tribal governments
- County governments
- State governments
- Public and Indian housing authorities
Nonprofit
- Nonprofits non-higher education with 501(c)(3)
- Nonprofits non-higher education without 501(c)(3)
- Other Native American tribal organizations
Business
- For-profit organizations other than small businesses
- Small businesses
Education
- Independent school districts
- Public and state institutions of higher education
- Private institutions of higher education
Miscellaneous
- Other
Additional information
Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Grantor contact information
Description
NIH Grants Information
grantsinfo@nih.gov
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.
Documents
Download all
| File name | Description | Last updated |
| --- | --- | --- |
| PAR-23-193-Full-Announcement.html | PAR-23-193 Full Announcement Text | May 19, 2023 02:38 PM UTC |
Link to additional information
https://grants.nih.gov/grants/guide/pa-files/PAR-23-193.html
Closing: April 3, 2026
Application process
This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates. View on Grants.gov
Award
$--
Program Funding
--
Expected awards
$--
Award Minimum
$--
Award Maximum
Funding opportunity number:
PAR-23-193
Cost sharing or matching requirement:
No Funding instrument type:
Grant
Opportunity Category:
Discretionary
Opportunity Category Explanation:
-- Category of Funding Activity:
Health
Income security and social services
Category Explanation:
--
History
Version:
1
Posted date:
May 19, 2023
Archive date:
May 9, 2026
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