USPTO Patent Application: Engineered Probiotics Expressing Anti-Inflammatory Molecules
Summary
The USPTO has published a patent application (US20260083783A1) from the University of Cincinnati for engineered probiotics that express anti-inflammatory molecules. The application details a genetically modified E. coli bacterium designed to produce a microbial anti-inflammatory molecule (MAM) protein.
What changed
This document is a USPTO patent application (US20260083783A1) filed by the University of Cincinnati, detailing engineered probiotics capable of expressing anti-inflammatory molecules. The application describes a modified E. coli bacterium, potentially a probiotic like E. coli Nissle 1917, engineered to express a specific microbial anti-inflammatory molecule (MAM) protein and a related plasmid.
As this is a patent application, it does not impose immediate compliance obligations on regulated entities. However, it signals potential future developments in therapeutic biotechnology. Companies involved in probiotic development, biotechnology, or the production of anti-inflammatory treatments should monitor the progress of this patent and related research for potential licensing opportunities or competitive insights.
Source document (simplified)
Engineered Probiotics Expressing Anti-Inflammatory Molecules
Application US20260083783A1 Kind: A1 Mar 26, 2026
Assignee
University of Cincinnati
Inventors
Nalinikanth Kotagiri, Tushar Madaan
Abstract
A genetically modified E. coli bacterium is provided where the bacterium expresses a microbial anti-inflammatory molecule (MAM) protein. In one embodiment, the bacterium is a probiotic. In another embodiment, the bacterium is modified is E. coli Nissle 1917. In one embodiment, the MAM protein has a sequence of [SEQ ID NO: 1]. In another embodiment, the bacterium expresses a plasmid having a sequence of [SEQ ID NO: 2].
CPC Classifications
A61K 35/741 A61P 9/00 C07K 14/195 C12N 15/70 C12R 2001/19
Filing Date
2023-09-13
Application No.
19111351
Named provisions
Related changes
Source
Classification
Who this affects
Taxonomy
Browse Categories
Get Pharma & Drug Safety alerts
Weekly digest. AI-summarized, no noise.
Free. Unsubscribe anytime.
Get alerts for this source
We'll email you when ChangeBridge: Patent Apps - Peptides (C07K) publishes new changes.