Polygon Therapeutics Anti-CD8 Antibodies for Immunotherapy
Summary
Polygon Therapeutics Anti-CD8 Antibodies for Immunotherapy
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Apr 11, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
ANTI-CD8 ALPHA DEPLETING ANTIBODIES
Application US20260098091A1 Kind: A1 Apr 09, 2026
Assignee
POLYGON THERAPEUTICS
Inventors
Tatiana MONSEUR, Mohamed ABOU ALI
Abstract
Novel anti-CD8α (cluster of differentiation 8 alpha) antibodies and antigen-binding fragments thereof, a fusion protein including the anti-CD8α antibodies and antigen-binding fragments thereof, and a nucleic acid molecule encoding the anti-CD8α antibodies and antigen-binding fragments thereof. Also, pharmaceutical compositions including the anti-CD8α antibodies and antigen-binding fragments thereof. Further, methods using the anti-CD8α antibodies and antigen-binding fragments thereof for treating CD8-related diseases and in vitro methods in which CD8a-expressing cells are depleted in a sample or in which CD8α is detected or quantified in a sample.
CPC Classifications
C07K 16/2815 A61K 39/3955 A61P 9/10 G01N 33/567 A61K 2039/505 C07K 14/70517 C07K 2317/56 C07K 2317/565 G01N 2333/70517
Filing Date
2025-12-08
Application No.
19411536
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