Single-Domain Antibodies That Bind ROR1
Summary
USPTO granted Patent US12600801B2 to Fred Hutchinson Cancer Center for single-domain antibodies binding receptor tyrosine kinase ROR1. The patent covers anti-cancer therapeutics, antibody-drug conjugates, multi-domain binding molecules, and cancer imaging/diagnostic agents. The patent contains 20 claims with inventors Jason Price, Colin E. Correnti, and James M. Olson.
What changed
USPTO granted Patent US12600801B2 to Fred Hutchinson Cancer Center covering single-domain antibodies that bind receptor tyrosine kinase ROR1. The antibodies have applications as anti-cancer therapeutics including antibody-drug conjugates, recombinant receptors, and cancer imaging/diagnostic agents.
For biotechnology and pharmaceutical companies, this patent establishes IP rights for ROR1-targeted cancer research and development. Parties interested in licensing this technology or developing competing therapies should monitor the patent portfolio and claim scope.
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Apr 14, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Single-domain antibodies that bind ROR1
Grant US12600801B2 Kind: B2 Apr 14, 2026
Assignee
Fred Hutchinson Cancer Center
Inventors
Jason Price, Colin E. Correnti, James M. Olson
Abstract
Single-domain antibodies that bind receptor tyrosine kinase (ROR1) are described. The single-domain antibodies can be used for multiple purposes including in research, imaging, diagnosis, and treatment of ROR1-related conditions. The disclosed single-domain antibodies can be used as anti-cancer therapeutics such as antibody-drug conjugates, multi-domain binding molecules, or recombinant receptors or can be used as cancer imaging/diagnostic agents.
CPC Classifications
C07K 16/468 C07K 16/30 C07K 2317/31 C07K 2317/52 C07K 2317/565 C07K 2317/569 C07K 2317/77 C07K 16/2809 C07K 16/2803 C07K 2317/22 C07K 2317/24 C07K 2317/73
Filing Date
2023-07-11
Application No.
18350617
Claims
20
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Source
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