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Polymer Nanoparticle Compositions for NF1 Treatment

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Summary

The USPTO published patent application US20260090998A1 covering methods of using block copolymer nanoparticles for delivering nucleic acids to treat Neurofibromatosis Type 1 (NF1). The application (filed October 2, 2025) names 12 inventors and discloses compositions and methods for in vivo therapeutic delivery using polymer nanoparticles.

What changed

The USPTO published a patent application for polymer nanoparticle compositions designed to deliver nucleic acids for treating NF1 (Neurofibromatosis Type 1). Application No. 19348578, filed October 2, 2025, and published April 2, 2026, discloses block copolymer nanoparticle technology for in vivo therapeutic delivery. The CPC classifications include A61K 9/5138 (nanoparticles), A61K 31/7088 (nucleic acids), and A61P 25/00 (nervous system diseases).

This publication is informational only and does not create compliance obligations. Pharmaceutical companies and researchers developing NF1 therapies may wish to review this application to assess potential freedom-to-operate considerations or avoid prior art conflicts.

Archived snapshot

Apr 2, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Applications

METHODS OF USING POLYMER NANOPARTICLE COMPOSITIONS FOR TREATING A DISEASE

Application US20260090998A1 Kind: A1 Apr 02, 2026

Inventors

Cherry Gupta, Caleb T. Hillrich, Ashlee J. Colbert, Emma K. Schmitz, Joseph Geers, Molly Kaufman, Daniel Garbark, Danielle J. Huk, Matthew Neal, Deeann Wallis, Robert Kesterson, Erik Westin

Abstract

The disclosure relates to methods of using block copolymer nanoparticles for in vivo therapeutic delivery, and methods therefor. More particularly, the invention relates to methods of using polymer nanoparticles for delivering nucleic acids for treating NF1.

CPC Classifications

A61K 9/5138 A61K 31/7088 A61P 25/00

Filing Date

2025-10-02

Application No.

19348578

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Last updated

Classification

Agency
USPTO
Published
April 2nd, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US20260090998A1

Who this affects

Applies to
Drug manufacturers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing 3345 Medical Device Manufacturing
Activity scope
Pharmaceutical Research Drug Development Gene Therapy
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Topics
Healthcare Intellectual Property

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