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Proton Pump Inhibitors for Inhibition of Aortic Valve Calcification

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Summary

USPTO published patent application US20260097026A1 for the use of proton pump inhibitors including prazole compounds to inhibit calcification of aortic valves, treating aortic sclerosis and stenosis. The application was filed on October 3, 2023, with inventors Arsenii Zabirnyk, Ingvar Jarle Vaage, and Kåre-Olav Stensløkken. The invention is classified under CPC codes A61K 31/4439 and A61P 9/10.

What changed

USPTO published patent application US20260097026A1 covering the use of proton pump inhibitors including prazole compounds for inhibiting aortic valve calcification and treating related diseases such as aortic sclerosis and stenosis. The application was filed on October 3, 2023 (Application No. 19115899) and published on April 9, 2026 as an A1 publication (original application as filed).\n\nAffected parties in the pharmaceutical and medical device sectors should monitor this application for potential blocking patents in the cardiovascular treatment space. Competitors developing similar proton pump inhibitor formulations for cardiovascular applications may need to conduct Freedom to Operate analyses or consider licensing discussions upon patent grant. This publication does not create immediate compliance obligations but signals potential future IP barriers in aortic valve calcification treatment.

What to do next

  1. Monitor patent prosecution status for potential licensing opportunities
  2. Review CPC classifications A61K 31/4439 and A61P 9/10 for Freedom to Operate analysis

Archived snapshot

Apr 11, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Applications

INHIBITION OF AORTIC VALVE CALCIFICATION

Application US20260097026A1 Kind: A1 Apr 09, 2026

Inventors

Arsenii Zabirnyk, Ingvar Jarle Vaage, Kåre-Olav Stensløkken

Abstract

The present invention relates to compounds useful for inhibiting calcification of aortic valves and to the treatment of diseases including aortic sclerosis and stenosis, and in particular to the use of the proton pump inhibitors including prazole compounds for the aforesaid treatments.

CPC Classifications

A61K 31/4439 A61P 9/10

Filing Date

2023-10-03

Application No.

19115899

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Last updated

Classification

Agency
USPTO
Published
April 9th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US20260097026A1

Who this affects

Applies to
Pharmaceutical companies Medical device makers Healthcare providers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Patent application publication Drug compound formulation Cardiovascular treatment research
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Pharmaceuticals Healthcare

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