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USPTO Patent Grant: Dopamine D3 Agonists for CNS Disorders

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Published March 24th, 2026
Detected March 24th, 2026
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Summary

The USPTO has granted patent US12582648B2 to Bioprojet Pharma for a method of treating central nervous system disorders, including restless leg syndrome and neurodegenerative diseases, using dopamine D3 partial agonists. The patent details specific applications and classifications related to these therapeutic uses.

What changed

The United States Patent and Trademark Office (USPTO) has issued patent US12582648B2 to Bioprojet Pharma. This patent covers a method for treating or inhibiting central nervous system disorders such as restless leg syndrome, binge eating, essential tremor, and neurodegenerative diseases. The method specifically utilizes dopamine D3 partial agonists, including those with D2 antagonist properties.

This patent grant signifies a new intellectual property asset in the therapeutic area of CNS disorders. While not a regulatory rule imposing obligations on other entities, it represents a significant development for Bioprojet Pharma in its drug development efforts. Compliance officers in the pharmaceutical sector should be aware of this patent as it pertains to the therapeutic landscape for CNS treatments.

Source document (simplified)

← USPTO Patent Grants

Method for treating central nervous system disorders using dopamine D3 partial agonists

Grant US12582648B2 Kind: B2 Mar 24, 2026

Assignee

BIOPROJET PHARMA

Inventors

Jeanne-Marie Lecomte, Jean Charles Schwartz, Isabelle Berrebi-Bertrand, Stéphane Krief, Xavier Ligneau, Isabelle Lecomte

Abstract

Disclosed is a method of using D3 partial agonists for treating or inhibiting the restless leg syndrome, binge eating, essential tremor and neurodegenerative diseases, in particular D3 partial agonists/D2 antagonists.

CPC Classifications

A61K 31/495 A61P 25/16 A61P 25/28 A61P 25/00

Filing Date

2021-05-04

Application No.

17922767

Claims

4

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Named provisions

Method for treating central nervous system disorders using dopamine D3 partial agonists

Classification

Agency
USPTO
Published
March 24th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US12582648B2

Who this affects

Applies to
Drug manufacturers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Drug Development
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
R&D
Topics
Central Nervous System Disorders Drug Development

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