Fusion antibody for presenting antigen-derived T cell epitope
Summary
USPTO granted Patent US12590156B2 to AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION for a fusion antibody composition designed to deliver viral antigen-derived CD8+ T cell antigen epitopes to target cell cytoplasm for presentation on major histocompatibility complex class I (MHC-I) molecules. The patent contains 22 claims covering the composition and its use in antigen presentation.
What changed
USPTO issued Patent US12590156B2 on March 31, 2026, granting AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION exclusive rights to a fusion antibody technology for delivering CD8+ T cell antigen epitopes to cell cytoplasm. The patent covers a composition comprising the fusion antibody and methods for presenting antigen-derived epitopes on MHC-I molecules. The invention was filed as Application No. 17796788 on February 5, 2021, with 22 claims allowed.
This patent grant does not impose immediate compliance obligations on other entities. Companies developing T cell-based immunotherapies, vaccines, or related fusion antibody technologies should review the patent claims to assess potential licensing needs or freedom-to-operate concerns. The granted patent provides the assignee with enforceable exclusive rights in the US for the claimed fusion antibody compositions and methods.
Source document (simplified)
Fusion antibody for presenting antigen-derived T cell antigen epitope or peptide containing same on cell surface, and composition comprising same
Grant US12590156B2 Kind: B2 Mar 31, 2026
Assignee
AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
Inventors
Yong Sung Kim, Jeong-Ah Kim, Keunok Jung, Seyoung Lee, Min-Jeong Son
Abstract
The present invention relates to: a composition for delivering a viral antigen-derived CD8+ T cell antigen epitope or a peptide comprising same to the cytoplasm of a target cell to thereby present the epitope or peptide to major histocompatibility complex class I (MAC-1), which is an antigen-presenting molecule on the cell surface; a composition comprising same; and a use thereof.
CPC Classifications
A61P 31/00
Filing Date
2021-02-05
Application No.
17796788
Claims
22
Named provisions
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