USPTO Patent Grant for Polypeptide Reagent Kit

ChangeBridge: Patent Grants - Peptides (C07K)

Published March 17th, 2026

Detected March 22nd, 2026

Summary

The USPTO has granted a patent (US12578329B2) to Shimadzu Corporation for a reagent kit containing polypeptides designed for detecting intermolecular interactions. The patent details specific amino acid sequences and their modifications for use in this kit.

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What changed

The United States Patent and Trademark Office (USPTO) has issued patent US12578329B2 to Shimadzu Corporation. This patent covers a reagent kit that includes a first and second polypeptide, each comprising specific amino acid sequences derived from SEQ ID NO: 1, with defined deletions and potential substitutions. The kit is designed for the detection of intermolecular interactions.

This grant represents a new intellectual property right for Shimadzu Corporation in the field of biotechnology and diagnostics. While patents do not impose direct regulatory obligations on other entities, they establish exclusive rights that may impact market entry, product development, and licensing strategies for companies operating in the pharmaceutical and biotechnology sectors. Compliance officers should be aware of this patent's existence as it pertains to research and development activities involving similar polypeptide reagents.

Source document (simplified)

← USPTO Patent Grants

Reagent kit containing polypeptide for use in detection of intermolecular interactions

Grant US12578329B2 Kind: B2 Mar 17, 2026

Assignee

SHIMADZU CORPORATION

Inventors

Yuki Ohmuro

Abstract

A reagent kit comprising a first polypeptide including a part in any one of amino acid sequences (A) to (C), and a second polypeptide including a part in any one of amino acid sequences (A) to (C), which are consistent of different sequences from a sequence of the first polypeptide;
(A) an amino acid sequence in SEQ ID NO: 1 with deletion of an amino acid sequence from position 1 to 69 and an amino acid sequence from position 204 to 221,(B) an amino acid sequence in SEQ ID NO: 1 with deletion of an amino acid sequence from position 1 to 69 and deletion or substitution of at least one of amino acid residues at positions 146 to 156,(C) the amino acid sequence (A) or (B) with further deletion of at least one of amino acid residues at positions 70 to 74.