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Reagent kit containing polypeptide for use in detection of intermolecular interactions

Grant US12578329B2 Kind: B2 Mar 17, 2026

Assignee

SHIMADZU CORPORATION

Inventors

Yuki Ohmuro

Abstract

A reagent kit comprising a first polypeptide including a part in any one of amino acid sequences (A) to (C), and a second polypeptide including a part in any one of amino acid sequences (A) to (C), which are consistent of different sequences from a sequence of the first polypeptide; (A) an amino acid sequence in SEQ ID NO: 1 with deletion of an amino acid sequence from position 1 to 69 and an amino acid sequence from position 204 to 221,(B) an amino acid sequence in SEQ ID NO: 1 with deletion of an amino acid sequence from position 1 to 69 and deletion or substitution of at least one of amino acid residues at positions 146 to 156,(C) the amino acid sequence (A) or (B) with further deletion of at least one of amino acid residues at positions 70 to 74.

CPC Classifications

G01N 33/535 G01N 21/763 G01N 33/543 C07K 19/00 C07K 2319/01 C12N 5/10 C12N 9/0069 C12N 15/09 C12Q 1/26

Filing Date

2022-05-19

Application No.

17748727

Claims

4