COMPOSITIONS AND METHODS FOR REDUCING RNA LEVELS
Application
US20260085311A1
Kind: A1
Mar 26, 2026
Inventors
Liana Lareau, Fyodor Urnov, Ma. Carmelle Catamura
Abstract
The present disclosure provides methods for reducing the level of an RNA transcript from a target nucleic acid. The present disclosure provides methods of treating a disease that results from or is caused by a toxic gain-of-function protein. The present disclosure provides systems and compositions for carrying out a method of the present disclosure.
CPC Classifications
C12N 15/113
A61K 38/00
A61K 48/00
C12N 9/1276
C12N 9/222
C12N 9/78
C12N 15/52
C12N 15/63
C12Y 207/07049
C12Y 305/04004
C12Y 305/04005
C12N 2310/20
Filing Date
2023-06-20
Application No.
18876098