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Patent Application for Agonistic TNF Receptor Binding Agents

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Published August 27th, 2025
Detected March 26th, 2026
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Summary

The USPTO has published a new patent application, US20260085126A1, for agonistic TNF receptor binding agents. The application, filed on August 27, 2025, by inventors including Ugur Sahin, details binding agents for TNF superfamily receptors and their potential medical uses.

What changed

This document is a publication of a new patent application (US20260085126A1) filed with the USPTO on August 27, 2025. The application describes agonistic binding agents that target receptors within the TNF superfamily, specifically those binding to at least two different receptors. The abstract highlights the potential use of these agents in medicine, as well as related nucleic acid molecules, cells, pharmaceutical compositions, and kits.

This filing represents a new intellectual property disclosure. While patent applications themselves do not impose direct regulatory obligations on companies, they signal innovation and potential future product development in the pharmaceutical and biotechnology sectors. Companies operating in these areas, particularly those involved in drug discovery and development related to immune response or inflammatory conditions, should be aware of this application as it may indicate emerging technologies or competitive research directions.

Source document (simplified)

← USPTO Patent Applications

AGONISTIC TNF RECEPTOR BINDING AGENTS

Application US20260085126A1 Kind: A1 Mar 26, 2026

Inventors

Ugur Sahin, Friederike Gieseke, Isil Altintas, David Satijn, Paul Parren

Abstract

The present invention relates to binding agents binding to receptors of the TNF superfamily, in particular binding agents binding to at least two different receptors of the TNF superfamily, as well as to their use in medicine. The present invention further relates to nucleic acid molecules encoding such binding agents, to cells comprising such nucleic acid molecules and to pharmaceutical compositions and kits.

CPC Classifications

C07K 16/2878 C07K 2317/31 C07K 2317/565 C07K 2317/75 C07K 2317/92

Filing Date

2025-08-27

Application No.

19311661

View original document →

Named provisions

Inventors Abstract CPC Classifications Filing Date Application No.

Classification

Agency
USPTO
Published
August 27th, 2025
Instrument
Notice
Legal weight
Non-binding
Stage
Draft
Change scope
Minor
Document ID
US20260085126A1

Who this affects

Applies to
Drug manufacturers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing 3254.1 Biotechnology
Activity scope
Drug Discovery Biotechnology Research
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Compliance frameworks
FDA 21 CFR Part 11
Topics
Intellectual Property Biotechnology

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