PARP1 Inhibitors and Uses Thereof
Summary
USPTO published patent application US20260098024A1 disclosing PARP1 inhibitor compounds and pharmaceutical compositions for cancer treatment. The application, filed on January 26, 2023 under application number 18833362, names six inventors including Robert L. Hoffman and Stephen W. Kaldor and covers compounds classified under C07D 401/12 and C07D 471/04.
What changed
USPTO published patent application US20260098024A1 disclosing novel PARP1 (poly ADP-ribose polymerase 1) inhibitor compounds and pharmaceutical compositions comprising said inhibitors for treating cancer. The application covers compounds classified under CPC subclasses C07D 401/12 and C07D 471/04, with claims directed to the inhibitor compounds, pharmaceutical formulations, and methods of treatment.
Pharmaceutical companies developing PARP inhibitors or cancer therapeutics should review the published claims to assess freedom-to-operate considerations. Competitors in the oncology drug development space should monitor this application and related filings for potential blocking patents. Research institutions and clinical investigators may find this IP landscape relevant for partnership or licensing discussions.
What to do next
- Monitor for patent grant status
- Conduct freedom-to-operate analysis for PARP1 inhibitor development
- Review published claims for competitive implications
Archived snapshot
Apr 9, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
PARP1 INHIBITORS AND USES THEREOF
Application US20260098024A1 Kind: A1 Apr 09, 2026
Inventors
Robert L. Hoffman, Porino Jinjo Va, Joseph Robert Pinchman, Lynnie Trzoss, Qing Dong, Stephen W. Kaldor
Abstract
Described herein are PARP1 inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of cancer.
CPC Classifications
C07D 401/12 A61K 31/496 A61K 31/498 A61P 35/00 C07D 471/04
Filing Date
2023-01-26
Application No.
18833362
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