Oligopeptide Inhibits Angiogenesis and Vascular Function
Summary
The USPTO published patent application US20260091078A1 covering an oligopeptide composition of 3-7 amino acids that inhibits angiogenesis and vascular function. The oligopeptide comprises defined sequence patterns with basic, small, polar, and hydrophobic amino acid residues. The application claims priority from July 7, 2020.
What changed
The USPTO published a patent application for an oligopeptide therapeutic composition with anti-angiogenic and vascular function-inhibiting properties. The claims cover oligopeptides of 3-7 amino acids with specific sequence motifs: X2-X3-X4 (3-mer), X1-X2-X3-X4 (4-mer), and X1-X2-X3-X4-X5-X6-X7 (7-mer), where positions are defined by amino acid properties (basic, small, polar, hydrophobic). The application is classified under A61K 38/08, A61P 9/00, A61P 27/02, and C07K 16/18.
This patent publication is informational for entities in the pharmaceutical and biotechnology sectors. Competitors developing peptide-based therapeutics targeting angiogenesis should conduct freedom-to-operate analyses and review this application during prior art searches. No compliance deadlines or regulatory obligations are imposed by this document.
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Apr 2, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
OLIGOPEPTIDE THAT INHIBITS ANGIOGENESIS AND VASCULAR FUNCTION
Application US20260091078A1 Kind: A1 Apr 02, 2026
Inventors
Jakob TRIEBEL, Thomas Bertsch, Marid del Carmen Clapp Jiminez L., Juan Pablo Robles Alvarez, Maria Magdalena Zamora Corona, Gonzalo Martinez de la Escalera Lorenzo
Abstract
An oligopeptide that inhibits angiogenesis and vascular function which oligonucleotide has a length of 3 to 7 amino acids and comprises or consists of the sequence X2-X3-X4, wherein X2 is a basic or amide amino acid, X3 is a small amino acid and X4 is a basic amino acid, charged at neutral pH or the sequence X1-X2-X3-X4, wherein X1 is a polar non-charged amino acid and X2, X3 and X4 are identical to X2, X3 and X4 in X2-X3-X4, or the sequence X1-X2-X3-X4-X5-X6-X7, wherein X1, X2, X3 and X4 are identical to X1, X2, X3 and X4 in X1-X2-X3-X4, X5 is a small amino acid, X6 is a hydrophobic amino acid and X7 is a hydrophobic amino acid.
CPC Classifications
A61K 38/08 A61P 9/00 A61P 27/02 C07K 16/18
Filing Date
2020-07-07
Application No.
17778396
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