Macrocycle and Hydrophobic Particle Method for Removing Polymers from Protein Solutions
Summary
USPTO published patent application US20260098055A1 for a method of removing free polymers from solutions containing hydrophobic proteins using macrocycles and/or hydrophobic particles. The application (CPC C07K 1/145) was filed September 7, 2023, with inventors including Barbara Maertens and colleagues. This pre-grant publication does not confer any enforceable rights.
What changed
USPTO published patent application US20260098055A1 for a method of removing free polymers from solutions containing hydrophobic proteins by contacting the solution with macrocycles and/or hydrophobic particles, forming a complex that is then removed from the solution. The application names Barbara Maertens, Jan Kubicek, Roland Fabis, Philipp Timo Hanisch, Sergej Balanda, Michael Erkelenz, and Nina Valeska Heckmann as inventors, with CPC classification C07K 1/145.\n\nR&D organizations and biotech/pharma companies developing protein purification methods should monitor this publication for competitive intelligence purposes. While pre-grant publications do not create enforceable exclusivity, they signal active innovation in protein sample preparation. No immediate compliance obligations arise from this publication; parties should await actual patent grant and claim examination before assessing IP landscape implications.
What to do next
- Monitor for updates on patent prosecution status
- Review claims for potential infringement risk if developing similar purification methods
Archived snapshot
Apr 9, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
REMOVAL OF POLYMERS FROM A SOLUTION BY USING MACROCYLCES AND/OR HYDROPHOBIC PARTICLES
Application US20260098055A1 Kind: A1 Apr 09, 2026
Inventors
Barbara Maertens, Jan Kubicek, Roland Fabis, Philipp Timo Hanisch, Sergej Balanda, Michael Erkelenz, Nina Valeska Heckmann
Abstract
A method for removing free polymers present in a solution containing a hydrophobic protein, wherein the method comprises (a) contacting the solution containing the free polymers not bound to the hydrophobic protein, with a macrocycle and/or a hydrophobic particle so that the free polymers bind to the macrocycle and/or hydrophobic particle to obtain a complex of said polymers and the macrocycle and/or hydrophobic particle, and (b) removing the complex of polymer and the macrocycle and/or hydrophobic protein from the solution. Macrocycles and a kit containing a macrocycle and/or hydrophobic particle to be employed in the method.
CPC Classifications
C07K 1/145
Filing Date
2023-09-07
Application No.
19112126
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