Lipid Particles Comprising Variant Paramyxovirus Attachment Glycoproteins
Summary
USPTO published patent application US20260098062A1 assigned to Sana Biotechnology, Inc. covering lipid particles comprising variant Paramyxovirus attachment glycoproteins with reduced glycosylation and methods for their production and use. The application (originally filed September 21, 2023) covers viral-based particles with modified G/H proteins and their therapeutic applications.
What changed
USPTO published Sana Biotechnology's patent application covering lipid particles, including viral-based particles, with variant Paramyxovirus attachment glycoproteins engineered to have reduced glycosylation. The application discloses methods for producing and modifying these particles and their therapeutic applications.
Affected parties in the biotechnology and gene therapy sectors should review the published claims for potential licensing needs or to assess freedom-to-operate for competing technologies involving viral-based delivery systems and glycoprotein engineering.
What to do next
- Monitor for patent issuance
- Review claims for freedom-to-operate analysis
Archived snapshot
Apr 11, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
LIPID PARTICLES COMPRISING VARIANT PARAMYXOVIRUS ATTACHMENT GLYCOPROTEINS AND USES THEREOF
Application US20260098062A1 Kind: A1 Apr 09, 2026
Assignee
Sana Biotechnology, Inc.
Inventors
Patricia CRUITE, Katherine Elizabeth SULLIVAN, Alexander Mark JUSTEN, Valeria BERLFEIN, Shirisha AMATYA, Albert Ruzo MATIAS, Kyle TRUDEAU, Matteo STOPPATO
Abstract
Provided herein are lipid particles, including viral-based particles, comprising Paramyxovirus glycoproteins having reduced glycosylation, and in some aspects, comprise variant G/H proteins. Also provided are methods for producing and modifying lipid particles, including viral-based particles, wherein the particle has reduced glycosylation of the G/H protein, as well as methods for using the particles.
CPC Classifications
C07K 14/005 C07K 16/2812 C07K 16/2815 C12N 15/86 C07K 2317/569 C07K 2317/622 C07K 2319/33 C12N 2740/15043 C12N 2740/15045 C12N 2760/18022
Filing Date
2023-09-21
Application No.
19113834
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Source
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