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High Density Sequencing Methods Patent Granted to Singular Genomics

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Summary

The USPTO granted patent US12600962B2 to Singular Genomics Systems, Inc. covering high density sequencing and multiplexed priming methods. The patent protects 30 claims for methods including sequencing overlapping amplification clusters, different polynucleotides immobilized on solid support, and three or more populations of polynucleotides on solid support. Inventors include Eli N. Glezer, Daan Witters, and Niek Van Wietmarschen.

What changed

The USPTO issued patent US12600962B2 to Singular Genomics Systems, Inc. for high density sequencing and multiplexed priming methods. The patent contains 30 claims covering methods of sequencing overlapping amplification clusters, different polynucleotides immobilized on solid support, and three or more populations of polynucleotides on solid support.

This patent grant establishes enforceable intellectual property rights for Singular Genomics in the high-throughput sequencing space. Competitors developing similar sequencing technologies should review this patent for potential infringement concerns and may need to seek licensing for any overlapping methods.

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Archived snapshot

Apr 16, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Grants

High density sequencing and multiplexed priming

Grant US12600962B2 Kind: B2 Apr 14, 2026

Assignee

Singular Genomics Systems, Inc.

Inventors

Eli N. Glezer, Daan Witters, Niek Van Wietmarschen

Abstract

Disclosed herein, inter alia, are methods and compositions for sequencing a plurality of template nucleic acids. In an aspect is provided a method of sequencing an overlapping amplification cluster, a method of sequencing different polynucleotide immobilized on a solid support, and a method of sequencing three or more populations of polynucleotides on a solid support.

CPC Classifications

C12N 15/1068 C12Q 1/6806 C12Q 1/6837 C12Q 1/6844 C12Q 1/6874

Filing Date

2023-01-13

Application No.

18154639

Claims

30

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Classification

Agency
USPTO
Published
April 14th, 2026
Instrument
Rule
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
US12600962B2

Who this affects

Applies to
Manufacturers Technology companies
Industry sector
3254.1 Biotechnology
Activity scope
Patent grants IP licensing Genomics technology
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Healthcare Pharmaceuticals

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