Changeflow GovPing Pharma & Drug Safety LANMODULIN ORTHOLOGS WITH IMPROVED RARE EARTH S...
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LANMODULIN ORTHOLOGS WITH IMPROVED RARE EARTH SEPARATION PERFORMANCE

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Summary

USPTO published patent application US20260098064A1 for lanmodulin orthologs (proteins) designed to bind rare earth metals with enhanced REE/REE selectivity. The application covers proteins with four EF hand motifs, methods of using the proteins, and devices/kits containing them. The invention has applications in rare earth element separation and processing.

What changed

USPTO published patent application US20260098064A1 for lanmodulin orthologs designed for rare earth metal binding. The proteins feature four EF hand motifs with 11-13 amino acid residues each, separated by 12-13 amino acid linkers, with enhanced REE/REE selectivity for separating different rare earth elements from each other.

For companies in mining, materials processing, or environmental remediation involving rare earth elements, this patent represents potential freedom-to-operate considerations. Entities developing or using rare earth separation technologies should review the patent claims to assess whether their processes or products may require licensing.

What to do next

  1. Monitor for patent issuance updates
  2. Review patent claims for potential infringement concerns

Archived snapshot

Apr 11, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Applications

LANMODULIN ORTHOLOGS WITH IMPROVED RARE EARTH SEPARATION PERFORMANCE

Application US20260098064A1 Kind: A1 Apr 09, 2026

Inventors

Joseph Alfred COTRUVO, Jr., Joseph Anthony MATTOCKS, Amie Kathleen BOAL, Jonathan JUNG, Chi-Yun LIN, Ziye DONG, Dan M. PARK, Wonseok CHOI

Abstract

Provided are proteins that bind rare earth metals. The proteins may have enhanced REE/REE selectivity. The proteins may have four EF hand motifs each having 11, 12, or 13 amino acids residues. Each EF hand motif is separated by 12 or 13 amino acid residues, where each amino acid residue is any canonical amino acid residue and at least one amino acid residue is a hydrophobic amino acid residue. When the EF hand motif has 12 amino acid residues, the motif may have the following sequence: X1-X2-X3-X4-X5-X6-X7-X8-X9-X10-X11-E. Also provided are devices and kits comprising a protein of the present disclosure. Also provided are methods of using the proteins and devices.

CPC Classifications

C07K 14/195 G01N 1/4077 G01N 33/1813

Filing Date

2023-09-18

Application No.

19112328

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Last updated

Classification

Agency
USPTO
Published
April 9th, 2026
Instrument
Rule
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
US20260098064A1

Who this affects

Applies to
Manufacturers Technology companies Mining companies
Industry sector
3254.1 Biotechnology
Activity scope
Patent filings Rare earth separation Protein engineering
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Biotechnology Environmental Protection

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