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Isotopically enriched psychedelic analogs for brain disorders

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Published April 2nd, 2026
Detected April 2nd, 2026
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Summary

The USPTO published patent application US20260092060A1 for isotopically enriched analogs of 2-bromo-LSD, LSD, ALD-52, and 1P-LSD developed by inventors Matthew Duncton and Samuel Clark. The compounds are directed toward treating neurologic and brain disorders. The application was filed on June 5, 2025, under Application No. 19228993.

What changed

The USPTO published a patent application covering isotopically enriched variants of classic psychedelic compounds including 2-bromo-LSD, LSD, ALD-52, and 1P-LSD. The claimed inventions include novel chemical compositions and methods for their use in treating neurologic and brain disorders. The patent is classified under CPC codes including C07D 457/06 (lysergic acid derivatives), A61K 31/48, A61P 25/28, and A61P 25/32 covering nervous system and neurological disorder treatments.

Pharmaceutical companies and researchers developing psychedelic-based therapeutics should review this application to assess potential freedom-to-operate considerations and competitive landscape. This represents an emerging patent filing in the psychedelic medicine space targeting neurological applications. No immediate compliance actions are required as this is a pending patent application, not an issued patent or regulatory requirement.

Source document (simplified)

← USPTO Patent Applications

ISOTOPICALLY ENRICHED ANALOGS OF 2-BROMO-LSD, LSD, ALD-52, AND 1P-LSD

Application US20260092060A1 Kind: A1 Apr 02, 2026

Inventors

Matthew DUNCTON, Samuel CLARK

Abstract

Disclosed herein are isotopically enriched compounds of 2-bromolysergic acid diethylamide, LSD, ALD-52, and 1P-LSD, as well as methods for their use in treating neurologic and brain disorders.

CPC Classifications

C07D 457/06 A61K 31/36 A61K 31/48 A61K 31/517 A61P 25/28 A61P 25/32

Filing Date

2025-06-05

Application No.

19228993

View original document →

Classification

Agency
USPTO
Published
April 2nd, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Draft
Change scope
Minor
Document ID
US20260092060A1

Who this affects

Applies to
Pharmaceutical companies Healthcare providers Patients
Industry sector
3254 Pharmaceutical Manufacturing 6211 Healthcare Providers
Activity scope
Patent Filings Drug Development Neurological Treatment Research
Geographic scope
United States US

Taxonomy

Primary area
Healthcare
Operational domain
Legal
Topics
Intellectual Property Pharmaceuticals

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