Treatments for Inflammation - Connexin Hemichannel Modulators
Summary
USPTO published patent application US20260091017A1 by inventors Shome, Mugisho, and Rupenthal for inflammation treatment compounds and methods using connexin hemichannel modulators, inflammasome modulators, and pannexin channel modulators. The application covers compositions for treating ocular and dermatological diseases characterized by inflammasome-mediated inflammation through systemic and topical administration. Application No. 19342361 filed September 26, 2025.
What changed
USPTO published patent application US20260091017A1 titled 'Treatments for Inflammation' disclosing novel compounds, compositions, and kits comprising connexin hemichannel modulators, inflammasome modulators, and/or pannexin channel modulators. The inventions cover methods for systemic and topical administration for treating ocular and dermatological diseases, disorders, and conditions characterized by inflammasome-mediated inflammation. Inventors include Avik Shome, Odunayo Omolola Mugisho, and Ilva D. Rupenthal.
This is a published patent application (Kind A1) that establishes a priority date of September 26, 2025. Pharmaceutical and biotechnology companies developing inflammation treatments should review the claims to assess potential freedom-to-operate implications or licensing opportunities. No compliance deadlines or regulatory obligations are associated with this publication for third parties.
Source document (simplified)
TREATMENTS FOR INFLAMMATION
Application US20260091017A1 Kind: A1 Apr 02, 2026
Inventors
AVIK SHOME, ODUNAYO OMOLOLA MUGISHO, ILVA D. RUPENTHAL
Abstract
The inventions relate to compounds, compositions and kits comprising connexin hemichannel modulators, inflammasome modulators, and/or pannexin channel modulators and new and improved methods comprising systemic and topical administration of such modulators for the treatment of ocular and dermatological diseases, disorders and conditions, including ocular and dermatological diseases, disorders and conditions characterized at least in part by inflammasome-mediated inflammationb.
CPC Classifications
A61K 31/352 A61K 31/573 A61K 45/06 A61P 27/02 A61P 29/00
Filing Date
2025-09-26
Application No.
19342361
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