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Treatments for Inflammation - Connexin Hemichannel Modulators

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Published April 2nd, 2026
Detected April 2nd, 2026
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Summary

USPTO published patent application US20260091017A1 by inventors Shome, Mugisho, and Rupenthal for inflammation treatment compounds and methods using connexin hemichannel modulators, inflammasome modulators, and pannexin channel modulators. The application covers compositions for treating ocular and dermatological diseases characterized by inflammasome-mediated inflammation through systemic and topical administration. Application No. 19342361 filed September 26, 2025.

What changed

USPTO published patent application US20260091017A1 titled 'Treatments for Inflammation' disclosing novel compounds, compositions, and kits comprising connexin hemichannel modulators, inflammasome modulators, and/or pannexin channel modulators. The inventions cover methods for systemic and topical administration for treating ocular and dermatological diseases, disorders, and conditions characterized by inflammasome-mediated inflammation. Inventors include Avik Shome, Odunayo Omolola Mugisho, and Ilva D. Rupenthal.

This is a published patent application (Kind A1) that establishes a priority date of September 26, 2025. Pharmaceutical and biotechnology companies developing inflammation treatments should review the claims to assess potential freedom-to-operate implications or licensing opportunities. No compliance deadlines or regulatory obligations are associated with this publication for third parties.

Source document (simplified)

← USPTO Patent Applications

TREATMENTS FOR INFLAMMATION

Application US20260091017A1 Kind: A1 Apr 02, 2026

Inventors

AVIK SHOME, ODUNAYO OMOLOLA MUGISHO, ILVA D. RUPENTHAL

Abstract

The inventions relate to compounds, compositions and kits comprising connexin hemichannel modulators, inflammasome modulators, and/or pannexin channel modulators and new and improved methods comprising systemic and topical administration of such modulators for the treatment of ocular and dermatological diseases, disorders and conditions, including ocular and dermatological diseases, disorders and conditions characterized at least in part by inflammasome-mediated inflammationb.

CPC Classifications

A61K 31/352 A61K 31/573 A61K 45/06 A61P 27/02 A61P 29/00

Filing Date

2025-09-26

Application No.

19342361

View original document →

Named provisions

Abstract CPC Classifications Inventors

Classification

Agency
USPTO
Published
April 2nd, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US20260091017A1

Who this affects

Applies to
Pharmaceutical companies Drug manufacturers Medical device makers
Industry sector
3254 Pharmaceutical Manufacturing 3254.1 Biotechnology
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Healthcare Pharmaceuticals Consumer Protection

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