HER2 HER3 Cancer Treatment Methods
Summary
The European Patent Office published patent application EP4048702A1 by Merus B.V. covering means and methods for treating HER2 and HER3 positive cancers. The application, filed by inventors Ernesto Isaac Wasserman and Leonardo Andres Sirulnik, discloses bispecific antibody compositions and treatment protocols. The patent designates all major European contracting states including Germany, France, UK, Italy, Spain, and the Netherlands.
What changed
EPO published patent application EP4048702A1 for Merus B.V., covering bispecific antibody compositions and methods for treating HER2 and HER3 positive cancers. The A1 publication includes the international search report and designates 32 European contracting states. IPC classifications indicate therapeutic applications (A61P 35/00) and protein compositions (C07K 16/32).
Pharmaceutical and biotechnology companies developing HER2/HER3 targeted therapies should review the patent claims for potential licensing requirements or freedom-to-operate concerns. The patent grants exclusivity in designated states upon grant. No immediate compliance actions are required as patent publications are informational; actual enforcement occurs through national courts upon patent grant.
What to do next
- Review patent claims for potential licensing or freedom-to-operate implications if developing HER2/HER3 targeted therapies
- Monitor patent prosecution for grant date and national phase deadlines in relevant jurisdictions
- Assess antibody composition claims for R&D planning purposes
Source document (simplified)
MEANS AND METHODS FOR TREATING SUBJECTS WITH HER2 AND HER3 POSITIVE CANCER
Publication EP4048702A1 Kind: A1 Mar 25, 2026
Applicants
Merus B.V.
Inventors
WASSERMAN, Ernesto Isaac, SIRULNIK, Leonardo Andres
IPC Classifications
C07K 16/32 20060101AFI20210430BHEP A61P 35/00 20060101ALI20210430BHEP
Designated States
AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR
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