Switchable Cas9 Nucleases and Uses Thereof - EP3693461A1
Summary
The European Patent Office granted Patent EP3693461A1 to President and Fellows of Harvard College covering switchable Cas9 nucleases and their uses. The invention, developed by David R. Liu and Johnny Hao Hu, is classified under C12N biotechnology codes. The patent is designated across 39 European states including major markets.
What changed
The EPO granted Patent EP3693461A1 for switchable Cas9 nucleases and uses thereof to President and Fellows of Harvard College. The invention, invented by David R. Liu and Johnny Hao Hu, covers controlled gene editing systems. The patent application was published under international patent classification C12N with designations across 39 European states.
Biotechnology companies engaged in gene editing research and development should evaluate whether their technologies fall within the scope of this patent. Parties may need to seek licensing from Harvard or assess potential design-around strategies to avoid infringement claims in designated EPO member states.
What to do next
- Monitor for updates on patent prosecution status
- Review licensing terms for Harvard's Cas9 technology
- Assess freedom-to-operate implications for gene editing programs
Archived snapshot
Apr 9, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
SWITCHABLE CAS9 NUCLEASES AND USES THEREOF
Publication EP3693461A1 Kind: A1 Apr 01, 2026
Applicants
President And Fellows Of Harvard College
Inventors
LIU, David R., HU, Johnny Hao
IPC Classifications
C12N 15/113 20100101AFI20200704BHEP C12N 9/22 20060101ALI20200704BHEP C12N 9/96 20060101ALI20200704BHEP C12N 15/10 20060101ALI20200704BHEP C12N 15/63 20060101ALI20200704BHEP C12N 15/01 20060101ALI20200704BHEP
Designated States
AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR
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Source
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