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Switchable Cas9 Nucleases and Uses Thereof - EP3693461A1

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Summary

The European Patent Office granted Patent EP3693461A1 to President and Fellows of Harvard College covering switchable Cas9 nucleases and their uses. The invention, developed by David R. Liu and Johnny Hao Hu, is classified under C12N biotechnology codes. The patent is designated across 39 European states including major markets.

What changed

The EPO granted Patent EP3693461A1 for switchable Cas9 nucleases and uses thereof to President and Fellows of Harvard College. The invention, invented by David R. Liu and Johnny Hao Hu, covers controlled gene editing systems. The patent application was published under international patent classification C12N with designations across 39 European states.

Biotechnology companies engaged in gene editing research and development should evaluate whether their technologies fall within the scope of this patent. Parties may need to seek licensing from Harvard or assess potential design-around strategies to avoid infringement claims in designated EPO member states.

What to do next

  1. Monitor for updates on patent prosecution status
  2. Review licensing terms for Harvard's Cas9 technology
  3. Assess freedom-to-operate implications for gene editing programs

Archived snapshot

Apr 9, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← EPO Patent Bulletin

SWITCHABLE CAS9 NUCLEASES AND USES THEREOF

Publication EP3693461A1 Kind: A1 Apr 01, 2026

Applicants

President And Fellows Of Harvard College

Inventors

LIU, David R., HU, Johnny Hao

IPC Classifications

C12N 15/113 20100101AFI20200704BHEP C12N 9/22 20060101ALI20200704BHEP C12N 9/96 20060101ALI20200704BHEP C12N 15/10 20060101ALI20200704BHEP C12N 15/63 20060101ALI20200704BHEP C12N 15/01 20060101ALI20200704BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR

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Last updated

Classification

Agency
EPO
Published
April 1st, 2026
Instrument
Notice
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
EP3693461A1

Who this affects

Applies to
Biotechnology companies Patent holders Research institutions
Industry sector
3254.1 Biotechnology
Activity scope
Patent licensing Gene editing research Biotech IP management
Geographic scope
European Union EU

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Healthcare Pharmaceuticals

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