Changeflow GovPing Pharma & Drug Safety Method for treating and modelling hearing loss
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Method for treating and modelling hearing loss

Favicon for changeflow.com ChangeBridge: Patent Grants - Biotech (C12N)
Published March 31st, 2026
Detected March 31st, 2026
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Summary

USPTO granted Patent US12590290B2 to Mackay Medical College for a method of treating hearing loss by providing transcription factors to induce generation of hair cell-like cells suitable for autologous cell replacement therapy. The patent, filed April 30, 2019, includes 13 claims with inventor Yi-Chao Hsu.

What changed

USPTO has granted Patent US12590290B2 to Mackay Medical College covering a method for treating hearing loss using a combination of transcription factors to generate hair cell-like cells for cell replacement therapy. The patent application (No. 17052818) was filed on April 30, 2019, and the patent includes 13 claims.

Patent holders should ensure this intellectual property is properly maintained and monitored for potential licensing opportunities or infringement concerns. Third parties interested in using this technology commercially should seek licensing agreements with Mackay Medical College. There is no immediate compliance action required for most entities—this is a patent grant that establishes exclusive rights rather than imposing regulatory obligations.

Source document (simplified)

← USPTO Patent Grants

Method for treating and modelling hearing loss

Grant US12590290B2 Kind: B2 Mar 31, 2026

Assignee

Mackay Medical College

Inventors

Yi-Chao Hsu

Abstract

A method for treating hearing loss in a subject in need thereof is provided. The method includes providing a combination of transcription factors to induce generation of a hair cell-like cell, thereby treating the hearing loss in the subject. The generated hair cell-like cells exhibit characteristic of mature functional cells that is useful in cell replacement therapy for autologous transplantation.

CPC Classifications

C12N 2501/00 C12N 5/062

Filing Date

2019-04-30

Application No.

17052818

Claims

13

View original document →

Source

Analysis generated by AI. Source diff and links are from the original.

Classification

Agency
USPTO
Published
March 31st, 2026
Instrument
Notice
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
US12590290B2

Who this affects

Applies to
Healthcare providers Educational institutions
Industry sector
3254.1 Biotechnology 3254 Pharmaceutical Manufacturing 6211 Healthcare Providers
Activity scope
Patent issuance Intellectual property protection
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Healthcare Biotechnology

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