Method for treating and modelling hearing loss
Summary
USPTO granted Patent US12590290B2 to Mackay Medical College for a method of treating hearing loss by providing transcription factors to induce generation of hair cell-like cells suitable for autologous cell replacement therapy. The patent, filed April 30, 2019, includes 13 claims with inventor Yi-Chao Hsu.
What changed
USPTO has granted Patent US12590290B2 to Mackay Medical College covering a method for treating hearing loss using a combination of transcription factors to generate hair cell-like cells for cell replacement therapy. The patent application (No. 17052818) was filed on April 30, 2019, and the patent includes 13 claims.
Patent holders should ensure this intellectual property is properly maintained and monitored for potential licensing opportunities or infringement concerns. Third parties interested in using this technology commercially should seek licensing agreements with Mackay Medical College. There is no immediate compliance action required for most entities—this is a patent grant that establishes exclusive rights rather than imposing regulatory obligations.
Source document (simplified)
Method for treating and modelling hearing loss
Grant US12590290B2 Kind: B2 Mar 31, 2026
Assignee
Mackay Medical College
Inventors
Yi-Chao Hsu
Abstract
A method for treating hearing loss in a subject in need thereof is provided. The method includes providing a combination of transcription factors to induce generation of a hair cell-like cell, thereby treating the hearing loss in the subject. The generated hair cell-like cells exhibit characteristic of mature functional cells that is useful in cell replacement therapy for autologous transplantation.
CPC Classifications
C12N 2501/00 C12N 5/062
Filing Date
2019-04-30
Application No.
17052818
Claims
13
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