BCD Gene Therapy Patent Grant
Summary
The USPTO granted Patent US12590320B2 to Reflection Biotechnologies Limited for gene therapy methods treating Bietti's Crystalline Dystrophy (BCD). The patent covers vectors delivering CYP4V2 protein to retinal pigment epithelial cells. This represents a routine patent grant establishing intellectual property rights for a biotechnology invention.
What changed
The USPTO issued B2 Patent US12590320B2 to Reflection Biotechnologies Limited, covering methods for treating ocular diseases including Bietti's Crystalline Dystrophy using gene therapy vectors that deliver CYP4V2 protein to retinal cells. The patent (CPC: C12N 15/86) was filed July 31, 2018, under Application No. 16635863, with 34 claims granted.
This is a routine patent grant notification establishing intellectual property protection. No compliance actions or deadlines apply. Pharmaceutical companies and healthcare providers developing gene therapies for inherited retinal diseases should note this patent when designing similar programs to avoid infringement. Legal and R&D teams should review the claims scope for potential licensing discussions.
Source document (simplified)
Cellular models of and therapies for ocular diseases
Grant US12590320B2 Kind: B2 Mar 31, 2026
Assignee
Reflection Biotechnologies Limited
Inventors
Richard R. Yang, Stephen H Tsang
Abstract
Provided herein are methods for treating or preventing diseases of the eye such as Bietti's Crystalline Dystrophy (BCD) using, for example, vectors for delivering a gene encoding a CYP4V2 protein to the retina (for example, to the retinal pigment epithelial (RPE) cells) or using cells comprising such vectors.
CPC Classifications
C12N 15/86
Filing Date
2018-07-31
Application No.
16635863
Claims
34
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