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GEVO patents NKR variants for isobutanol production

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GEVO patents NKR variants for isobutanol production

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Apr 7, 2026

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NKR variants for increased production of isobutanol

Grant US12595466B2 Kind: B2 Apr 07, 2026

Assignee

GEVO, INC.

Inventors

Christopher Smith, Timothy Hanly, Jeanne Benoit

Abstract

The present invention relates to recombinant microorganisms comprising at least one nucleic acid molecule encoding a ketol-acid reductoisomerase (KARI) or modified NADH-dependent variant thereof, wherein said KARI is at least about 60% identical to SEQ ID NO: 2. In various aspects of the invention, the recombinant microorganisms may comprise an isobutanol producing metabolic pathway and can be used in methods of making isobutanol.

CPC Classifications

C12P 7/16 C12N 9/0006 C12N 15/52 C12Y 101/01086

Filing Date

2021-03-05

Application No.

17909353

Claims

10

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