Immune Cells Overexpressing Cell Signaling Regulatory Factor and Use Thereof
Summary
The European Patent Office published patent application EP4105232A1 on March 25, 2026. The application covers engineered immune cells overexpressing cell signaling regulatory factors for therapeutic use. Applicants are Beijing Yongtai Ruike Biotechnology Company Ltd and Pharos Vaccine Inc. The filing is designated across 31 European states including DE, FR, GB, IT, and NL.
What changed
The EPO published international patent application EP4105232A1 titled 'Immune Cells Overexpressing Cell Signaling Regulatory Factor Introduced from Outside and Use Thereof.' The application covers engineered immune cells with modified cell signaling regulatory factor expression for therapeutic applications, including cancer treatment (A61P 35/00). Inventors include KIM Hoeon, JEON Choonju, WANG Yu, and JUNG Namchul. The filing covers multiple therapeutic protein classifications (C07K 16/28, C07K 14/725, C12N 5/0783) and is designated for all 31 EPO member states.
This is a routine patent publication providing public notice of the application. No compliance actions are required from pharmaceutical or biotechnology companies. Entities developing similar immune cell therapies should review the application claims to assess potential patent landscape implications. Freedom-to-operate analyses may be warranted for companies working in comparable CAR-T or immune cell engineering spaces.
Source document (simplified)
IMMUNE CELLS OVEREXPRESSING CELL SIGNALING REGULATORY FACTOR INTRODUCED FROM OUTSIDE AND USE THEREOF
Publication EP4105232A1 Kind: A1 Mar 25, 2026
Applicants
Beijing Yongtai Ruike Biotechnology Company Ltd, Pharos Vaccine Inc.
Inventors
KIM, Hoeon, JEON, Choonju, WANG, Yu, JUNG, Namchul
IPC Classifications
C07K 16/28 20060101AFI20230906BHEP C07K 14/705 20060101ALI20230906BHEP C07K 14/725 20060101ALI20230906BHEP C12N 15/86 20060101ALI20230906BHEP C12N 15/85 20060101ALI20230906BHEP C07K 14/495 20060101ALI20230906BHEP A61K 39/00 20060101ALI20230906BHEP A61K 38/00 20060101ALI20230906BHEP A61K 48/00 20060101ALI20230906BHEP A61P 35/00 20060101ALI20230906BHEP C07K 14/47 20060101ALI20230906BHEP C07K 16/30 20060101ALI20230906BHEP C07K 16/32 20060101ALI20230906BHEP C12N 5/0783 20100101ALI20230906BHEP
Designated States
AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR
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