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Immune Cells Overexpressing Cell Signaling Regulatory Factor and Use Thereof

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Published March 25th, 2026
Detected April 1st, 2026
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Summary

The European Patent Office published patent application EP4105232A1 on March 25, 2026. The application covers engineered immune cells overexpressing cell signaling regulatory factors for therapeutic use. Applicants are Beijing Yongtai Ruike Biotechnology Company Ltd and Pharos Vaccine Inc. The filing is designated across 31 European states including DE, FR, GB, IT, and NL.

What changed

The EPO published international patent application EP4105232A1 titled 'Immune Cells Overexpressing Cell Signaling Regulatory Factor Introduced from Outside and Use Thereof.' The application covers engineered immune cells with modified cell signaling regulatory factor expression for therapeutic applications, including cancer treatment (A61P 35/00). Inventors include KIM Hoeon, JEON Choonju, WANG Yu, and JUNG Namchul. The filing covers multiple therapeutic protein classifications (C07K 16/28, C07K 14/725, C12N 5/0783) and is designated for all 31 EPO member states.

This is a routine patent publication providing public notice of the application. No compliance actions are required from pharmaceutical or biotechnology companies. Entities developing similar immune cell therapies should review the application claims to assess potential patent landscape implications. Freedom-to-operate analyses may be warranted for companies working in comparable CAR-T or immune cell engineering spaces.

Source document (simplified)

← EPO Patent Bulletin

IMMUNE CELLS OVEREXPRESSING CELL SIGNALING REGULATORY FACTOR INTRODUCED FROM OUTSIDE AND USE THEREOF

Publication EP4105232A1 Kind: A1 Mar 25, 2026

Applicants

Beijing Yongtai Ruike Biotechnology Company Ltd, Pharos Vaccine Inc.

Inventors

KIM, Hoeon, JEON, Choonju, WANG, Yu, JUNG, Namchul

IPC Classifications

C07K 16/28 20060101AFI20230906BHEP C07K 14/705 20060101ALI20230906BHEP C07K 14/725 20060101ALI20230906BHEP C12N 15/86 20060101ALI20230906BHEP C12N 15/85 20060101ALI20230906BHEP C07K 14/495 20060101ALI20230906BHEP A61K 39/00 20060101ALI20230906BHEP A61K 38/00 20060101ALI20230906BHEP A61K 48/00 20060101ALI20230906BHEP A61P 35/00 20060101ALI20230906BHEP C07K 14/47 20060101ALI20230906BHEP C07K 16/30 20060101ALI20230906BHEP C07K 16/32 20060101ALI20230906BHEP C12N 5/0783 20100101ALI20230906BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR

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Source

Analysis generated by AI. Source diff and links are from the original.

Classification

Agency
EPO
Published
March 25th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
EP4105232A1

Who this affects

Applies to
Drug manufacturers Investors Healthcare providers
Industry sector
3254.1 Biotechnology
Activity scope
Patent Filing
Geographic scope
European Union EU

Taxonomy

Primary area
Intellectual Property
Operational domain
Research and Development
Topics
Healthcare Pharmaceuticals

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