Engineered Adeno-Associated Virus Capsid Patent
Summary
The European Patent Office published application EP4139443A2 for an engineered adeno-associated virus (AAV) capsid by Tenaya Therapeutics. The patent application covers AAV capsid proteins modified for enhanced gene therapy delivery, with inventors Christopher A. Reid and Ze Cheng. The application is designated across 36 European states.
What changed
The EPO published patent application EP4139443A2 for an engineered adeno-associated virus capsid developed by Tenaya Therapeutics. The application covers AAV capsid proteins modified through protein engineering for improved gene therapy vector properties. Inventors Christopher A. Reid and Ze Cheng are listed. The patent is classified under C07K 14/005 (peptides, specifically viral proteins) and other related IPC codes including C12N 15/86 (viral vectors) and A61K 48/00 (gene therapy preparations).
For gene therapy developers and biotechnology companies working with AAV-based vectors, this patent grant establishes intellectual property rights that may affect freedom-to-operate considerations. Companies developing AAV gene therapy products should review the patent claims to assess potential licensing requirements or design-around strategies, particularly in the designated European states.
What to do next
- Review patent claims for freedom-to-operate analysis
- Assess AAV capsid technology competition landscape
Archived snapshot
Apr 8, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
ADENO-ASSOCIATED VIRUS WITH ENGINEERED CAPSID
Publication EP4139443A2 Kind: A2 Apr 01, 2026
Applicants
Tenaya Therapeutics, Inc.
Inventors
REID, Christopher A., CHENG, Ze
IPC Classifications
C07K 14/005 20060101AFI20240709BHEP C12N 15/86 20060101ALI20240709BHEP C12N 7/01 20060101ALI20240709BHEP A61K 48/00 20060101ALI20240709BHEP A61P 9/00 20060101ALI20240709BHEP
Designated States
AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR
Named provisions
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Source
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