Changeflow GovPing Pharma & Drug Safety Doxycycline Mouthwash for COVID-19 Prevention
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Doxycycline Mouthwash for COVID-19 Prevention

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Summary

USPTO published patent application US20260091045A1 for a preventative mouthwash containing doxycycline (100-400mg dosage) for COVID-19 infection prevention. Inventor Bruce Roseman's application describes a gargling method using 5-20mL of the mouthwash twice daily for 5-10 days. The application was filed October 2, 2024 and published April 2, 2026.

What changed

The USPTO published patent application US20260091045A1 titled 'Preventative Mouthwash Containing Doxycycline and Method of Preventing COVID Infection' filed by inventor Bruce Roseman. The application claims a preventative mouthwash composition comprising doxycycline hyclate (100-400mg antimicrobial dosage) dissolved in purified water, with optional benzaldehyde flavoring, used in 5-20mL gargling doses. The claimed method involves gargling twice daily (every 12 hours) for 5-10 consecutive days.

This is a patent application publication, not a regulatory requirement. No compliance actions are required by regulated entities. Pharmaceutical manufacturers or healthcare providers interested in potential licensing or development of this product should monitor the patent prosecution process. The application is classified under CPC codes A61K 31/65 (antibiotic compositions) and A61K 9/006 (liquid oral dosage forms).

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Apr 3, 2026

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← USPTO Patent Applications

PREVENTATIVE MOUTHWASH CONTAINING DOXYCYCLINE AND METHOD OF PREVENTING COVID INFECTION USING THE PREVENTATIVE MOUTHWASH

Application US20260091045A1 Kind: A1 Apr 02, 2026

Inventors

Bruce Roseman

Abstract

A preventative mouthwash includes doxycycline as an active ingredient, and sufficient solvent (such as purified water) to dissolve an antimicrobial oral dosage of the doxycycline into a gargling dosage of the mouthwash. The antimicrobial oral dosage may be at least 100 milligrams (mg) of the doxycycline (such as 400 mg). The gargling dosage may be between 5 milliliters (mL) and 20 mL of the mouthwash (such as 5 mL). The mouthwash may further include a flavoring agent (such as benzaldehyde) to improve taste. A method of preventing COVID infection includes gargling the preventative mouthwash, and repeating the gargling twice a day (such as every 12 hours) for several (such as between 5 and 10, like 7) consecutive days. A method of formulating the preventative mouthwash includes dissolving doxycycline hyclate in purified water to create a liquid solution, and dissolving a flavoring agent in the liquid solution to create the mouthwash.

CPC Classifications

A61K 31/65 A61K 9/006

Filing Date

2024-10-02

Application No.

18904100

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Named provisions

Abstract Inventors CPC Classifications Filing Date Application No.

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Classification

Agency
USPTO
Published
April 2nd, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US20260091045A1

Who this affects

Applies to
Pharmaceutical companies Healthcare providers Patients
Industry sector
3254 Pharmaceutical Manufacturing 6211 Healthcare Providers
Activity scope
Pharmaceutical Manufacturing Drug Formulation Patent Filing
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Topics
Healthcare Intellectual Property

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