Changeflow GovPing Pharma & Drug Safety USPTO Patent Grant: Dapansutrile for Breast Can...
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USPTO Patent Grant: Dapansutrile for Breast Cancer Treatment

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Published March 24th, 2026
Detected March 24th, 2026
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Summary

The USPTO has granted patent US12582628B2 to Olatec Therapeutics, Inc. for a method of treating breast cancer using dapansutrile, optionally in combination with a checkpoint inhibitor. The patent covers methods of treatment and has an effective date of March 24, 2026.

What changed

The United States Patent and Trademark Office (USPTO) has granted patent US12582628B2 to Olatec Therapeutics, Inc. The patent, titled "Methods for treating breast cancer," claims a method of treating breast cancer by administering dapansutrile, or a pharmaceutically acceptable solvate thereof. The method optionally includes the co-administration of a checkpoint inhibitor. The patent's effective date is March 24, 2026.

This patent grant is primarily an informational notice for entities involved in pharmaceutical research and development, particularly in oncology. While it does not impose new compliance obligations, it signifies intellectual property protection for a specific therapeutic approach. Companies operating in this space should be aware of this granted patent as it may affect their freedom to operate or potential licensing opportunities related to dapansutrile and its use in combination therapy for breast cancer.

Source document (simplified)

← USPTO Patent Grants

Methods for treating breast cancer

Grant US12582628B2 Kind: B2 Mar 24, 2026

Assignee

OLATEC THERAPEUTICS, INC.

Inventors

Charles A. Dinarello, Isak Tengesdal

Abstract

The present invention is directed to a method of treating breast cancer. The method comprises administering to a subject in need thereof an effective amount of dapansutrile, or a pharmaceutically acceptable solvate thereof. The method optionally comprises further administering to the subject an effective amount of a checkpoint inhibitor.

CPC Classifications

A61K 31/275 A61K 39/3955 A61P 35/00

Filing Date

2022-04-13

Application No.

17659121

Claims

7

View original document →

Named provisions

Methods for treating breast cancer

Classification

Agency
USPTO
Published
March 24th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US12582628B2

Who this affects

Applies to
Drug manufacturers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Drug Development Cancer Treatment
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
R&D
Compliance frameworks
FDA 21 CFR Part 11 GxP
Topics
Oncology Drug Development

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