The EPO published Conagen Inc.'s patent application (EP3941961A1) for a biosynthetic method of producing gamma- and delta-lactones using engineered cytochrome P450 enzymes with subterminal hydroxylase activity. The application covers processes using C12N 15/52 classified enzymes, with applications in C08G 63/06 and C08G 63/08 polymer production. The designated contracting states include all major European markets (DE, FR, GB, IT, ES, NL, BE, etc.).\n\nThis patent publication does not impose compliance obligations on third parties. Competitors in the lactone/flavor compound manufacturing space should review the claims to assess potential freedom-to-operate implications for their own biosynthetic production processes. No immediate regulatory action is required; however, companies developing similar enzymatic lactone synthesis methods may need to consider licensing or design-around strategies.