Changeflow GovPing Pharma & Drug Safety Anti-C5 Agent for Treatment of Dry AMD or Geogr...
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Anti-C5 Agent for Treatment of Dry AMD or Geographic Atrophy

Favicon for changeflow.com ChangeBridge: EPO Bulletin - Biotech (C12N)
Published March 25th, 2026
Detected April 1st, 2026
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Summary

The European Patent Office published patent application EP4048288A1 for Astellas US LLC, covering an anti-C5 agent formulation for treating dry age-related macular degeneration (AMD) or geographic atrophy secondary to dry AMD. The invention relates to compositions comprising C12N 15/115 nucleic acid sequences with A61K 31/712 classifications, filed by inventor Rezaei K.A. The patent designates all 31 EPO contracting states including Germany, France, UK, Italy, Spain, and other EU member states.

What changed

EPO published patent application EP4048288A1 for Astellas US LLC's anti-C5 agent targeting dry AMD and geographic atrophy. The application covers nucleic acid compositions (C12N 15/115) with various pharmaceutical formulations (A61K 31/712, A61K 31/7088, A61K 31/713) for ocular administration. This is a standard patent publication under the EPC, designating 31 European contracting states.

Pharmaceutical companies developing complement pathway inhibitors for ophthalmic indications should review this publication for potential freedom-to-operate implications. Patent applicants and competitors in the dry AMD therapeutic space should assess claim scope and prosecution history once the application proceeds. No compliance deadlines apply to this publication notice.

Source document (simplified)

← EPO Patent Bulletin

ANTI-C5 AGENT FOR TREATMENT OF DRY AGE-RELATED MACULAR DEGENERATION (AMD) OR GEOGRAPHIC ATROPHY SECONDARY TO DRY AMD

Publication EP4048288A1 Kind: A1 Mar 25, 2026

Applicants

Astellas US LLC

Inventors

REZAEI, Kourous A.

IPC Classifications

A61K 31/712 20060101AFI20231024BHEP A61P 27/02 20060101ALI20231024BHEP A61K 31/7088 20060101ALI20231024BHEP A61K 9/00 20060101ALI20231024BHEP A61K 31/713 20060101ALI20231024BHEP A61K 47/60 20170101ALI20231024BHEP C12N 15/115 20100101ALI20231024BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR

View original document →

Named provisions

A61K 31/712 - Anti-C5 agent compositions A61P 27/02 - Ophthalmic compositions C12N 15/115 - Nucleic acid aptamers

Source

Analysis generated by AI. Source diff and links are from the original.

Classification

Agency
EPO
Published
March 25th, 2026
Instrument
Notice
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
EP4048288A1

Who this affects

Applies to
Pharmaceutical companies Healthcare providers
Industry sector
3254 Pharmaceutical Manufacturing 3254.1 Biotechnology
Activity scope
Patent Filing Biotechnology Pharmaceutical Development
Geographic scope
European Union EU

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Healthcare Pharmaceuticals

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