Anti-C5 Agent for Treatment of Dry AMD or Geographic Atrophy
Summary
The European Patent Office published patent application EP4048288A1 for Astellas US LLC, covering an anti-C5 agent formulation for treating dry age-related macular degeneration (AMD) or geographic atrophy secondary to dry AMD. The invention relates to compositions comprising C12N 15/115 nucleic acid sequences with A61K 31/712 classifications, filed by inventor Rezaei K.A. The patent designates all 31 EPO contracting states including Germany, France, UK, Italy, Spain, and other EU member states.
What changed
EPO published patent application EP4048288A1 for Astellas US LLC's anti-C5 agent targeting dry AMD and geographic atrophy. The application covers nucleic acid compositions (C12N 15/115) with various pharmaceutical formulations (A61K 31/712, A61K 31/7088, A61K 31/713) for ocular administration. This is a standard patent publication under the EPC, designating 31 European contracting states.
Pharmaceutical companies developing complement pathway inhibitors for ophthalmic indications should review this publication for potential freedom-to-operate implications. Patent applicants and competitors in the dry AMD therapeutic space should assess claim scope and prosecution history once the application proceeds. No compliance deadlines apply to this publication notice.
Source document (simplified)
ANTI-C5 AGENT FOR TREATMENT OF DRY AGE-RELATED MACULAR DEGENERATION (AMD) OR GEOGRAPHIC ATROPHY SECONDARY TO DRY AMD
Publication EP4048288A1 Kind: A1 Mar 25, 2026
Applicants
Astellas US LLC
Inventors
REZAEI, Kourous A.
IPC Classifications
A61K 31/712 20060101AFI20231024BHEP A61P 27/02 20060101ALI20231024BHEP A61K 31/7088 20060101ALI20231024BHEP A61K 9/00 20060101ALI20231024BHEP A61K 31/713 20060101ALI20231024BHEP A61K 47/60 20170101ALI20231024BHEP C12N 15/115 20100101ALI20231024BHEP
Designated States
AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR
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