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Cell Reprogramming Methods, Integration-Free, iPSCs

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Summary

Cell Reprogramming Methods, Integration-Free, iPSCs

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Apr 15, 2026

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Methods and compositions for reprogramming cells

Grant US12600968B2 Kind: B2 Apr 14, 2026

Assignee

The Regents of the University of Colorado, a body corporate

Inventors

Igor Kogut, Dennis R. Roop, Ganna Bilousova

Abstract

The present disclosure relates to methods and compositions for reprogramming cells to a pluripotent state. In particular, it relates to an integration- and feeder cell-free method for reprogramming primary human fibroblast cells to induced pluripotent stem cells (iPSCs).

CPC Classifications

C12N 15/113 C12N 5/0652 C12N 5/0696 C12N 9/22 C12N 15/11 C12N 15/907 C12N 2310/141 C12N 2310/20 C12N 2330/31 C12N 2500/60 C12N 2501/115 C12N 2501/602 C12N 2501/603 C12N 2501/604 C12N 2501/605 C12N 2501/606 C12N 2501/608 C12N 2501/65 C12N 2506/1307 C12N 2510/00 C12N 2800/80 A61K 31/713 A61K 35/28 A61P 17/00

Filing Date

2022-07-20

Application No.

17869514

Claims

20

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