Organoid Culture Compositions and Methods from Cryogenically Preserved Tissue

USPTO granted patent US12600953B2 to The Regents of the University of Michigan on April 14, 2026, establishing intellectual property rights for compositions and methods relating to organoid cultures from cryogenically preserved tissue. The patent, with inventors Jason Spence, Yu-Hwai Tsai, Michael Czerwinski, and John Kao, contains eight claims covering the organoid culture establishment techniques.

Affected parties including biotechnology companies, research institutions, and pharmaceutical firms developing organoid-based technologies should evaluate whether their products or methods may fall within the scope of these claims. Parties may wish to assess licensing opportunities or design-around strategies to avoid potential infringement.