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Anti-follicle stimulating hormone receptor antibodies and methods of treatment

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Summary

USPTO granted Patent US12595293B2 to The Wistar Institute covering isolated antibodies and antigen-binding fragments that specifically bind to Follicle Stimulating Hormone Receptor (FSHR), along with methods for treating diseases by administering these antibodies. The patent includes 14 claims and covers compositions for cancer treatment applications.

What changed

USPTO issued Patent No. US12595293B2 for anti-FSHR antibodies developed by inventors Alfredo Perales-Puchalt and David B. Weiner at The Wistar Institute. The patent grants exclusive rights to isolated antibodies that specifically bind to the follicle stimulating hormone receptor, as well as methods of treating diseases by administering these antibody compositions.

For pharmaceutical companies and biotechnology firms developing antibody therapeutics targeting FSHR or related cancer immunotherapies, this patent establishes intellectual property barriers requiring licensing negotiations or design-around strategies. Researchers and developers in the oncology and reproductive health spaces should conduct freedom-to-operate analyses before initiating related R&D programs.

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Archived snapshot

Apr 7, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Grants

Anti-follicle stimulating hormone receptor antibodies

Grant US12595293B2 Kind: B2 Apr 07, 2026

Assignee

The Wistar Institute

Inventors

Alfredo Perales-Puchalt, David B. Weiner

Abstract

The present invention relates to an isolated antibody or antigen binding fragment thereof that bind specifically to the Follicle Stimulating Hormone Receptor (FSHR). Also provided are methods for treating a disease in a subject comprising administering to the subject an isolated antibody or antibody fragment thereof that binds FSHR.

CPC Classifications

C07K 16/2869 A61K 45/06 A61K 47/6803 A61K 47/6849 A61K 2039/505 A61K 2039/54 A61P 35/00

Filing Date

2019-08-09

Application No.

17267331

Claims

14

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Last updated

Classification

Agency
USPTO
Published
April 7th, 2026
Instrument
Notice
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
US12595293B2

Who this affects

Applies to
Pharmaceutical companies Drug manufacturers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Biologic patent licensing Therapeutic antibody development
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Pharmaceuticals Medical Devices

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