Changeflow GovPing Pharma & Drug Safety USPTO Grants Patent for Anti-CD73 Antibody and Use
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USPTO Grants Patent for Anti-CD73 Antibody and Use

Favicon for changeflow.com ChangeBridge: Patent Grants - Peptides (C07K)
Published March 24th, 2026
Detected March 24th, 2026
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Summary

The United States Patent and Trademark Office (USPTO) has granted patent US12583933B2 to BIOTHEUS INC. for an anti-CD73 antibody and its use in enhancing immune response and treating tumors. The patent was filed on August 28, 2020, and is effective March 24, 2026.

What changed

The USPTO has issued a patent (US12583933B2) to BIOTHEUS INC. for an anti-CD73 antibody or antigen-binding fragment thereof, along with related nucleic acid molecules, immunoconjugates, bispecific molecules, and pharmaceutical compositions. The patent also covers the use of these agents in enhancing immune response and treating tumors. This grant signifies a new intellectual property right for the assignee concerning novel therapeutic agents in the field of immunology and disease therapy.

This patent grant does not impose new compliance obligations on regulated entities. However, it establishes exclusive rights for BIOTHEUS INC. regarding the patented technology. Companies operating in the pharmaceutical and biotechnology sectors, particularly those involved in cancer immunotherapy or developing treatments targeting CD73, should be aware of this patent to avoid potential infringement and to inform their own research and development strategies.

Source document (simplified)

← USPTO Patent Grants

Anti-CD73 antibody and use thereof

Grant US12583933B2 Kind: B2 Mar 24, 2026

Assignee

BIOTHEUS INC.

Inventors

Liang Du, Hongyan Zhang, Lina Jin, Yali Chen, Jijun Yuan, Zhenqing Zhang, Xiaoniu Miao, Weifeng Huang, Yunli Jia

Abstract

The present invention relates to the field of disease therapy and immunology. Specifically, disclosed are an anti-CD73 antibody or an antigen-binding fragment thereof, a nucleic acid molecule encoding same, an immunoconjugate comprising same, a bispecific molecule and a pharmaceutical composition, as well as use thereof in enhancing immune response and/or treating tumors.

CPC Classifications

C07K 16/2896 C07K 2317/31 C07K 2317/565 C07K 2317/77 C07K 2317/24 C07K 2317/33 C07K 2317/73 C07K 2317/76 C07K 2317/92 A61P 35/00 G01N 33/57492 G01N 2333/70596 G01N 33/6872 G01N 33/574 A61K 2039/505

Filing Date

2020-08-28

Application No.

17924941

Claims

20

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Named provisions

Abstract Claims

Source

Analysis generated by AI. Source diff and links are from the original.

Classification

Agency
USPTO
Published
March 24th, 2026
Instrument
Rule
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
US12583933B2

Who this affects

Applies to
Drug manufacturers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing 3254.1 Biotechnology
Activity scope
Drug Development Immunotherapy
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Compliance
Compliance frameworks
GxP
Topics
Immunology Oncology

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