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Anti-CD73 antibody and use thereof

Grant US12583933B2 Kind: B2 Mar 24, 2026

Assignee

BIOTHEUS INC.

Inventors

Liang Du, Hongyan Zhang, Lina Jin, Yali Chen, Jijun Yuan, Zhenqing Zhang, Xiaoniu Miao, Weifeng Huang, Yunli Jia

Abstract

The present invention relates to the field of disease therapy and immunology. Specifically, disclosed are an anti-CD73 antibody or an antigen-binding fragment thereof, a nucleic acid molecule encoding same, an immunoconjugate comprising same, a bispecific molecule and a pharmaceutical composition, as well as use thereof in enhancing immune response and/or treating tumors.

CPC Classifications

C07K 16/2896 C07K 2317/31 C07K 2317/565 C07K 2317/77 C07K 2317/24 C07K 2317/33 C07K 2317/73 C07K 2317/76 C07K 2317/92 A61P 35/00 G01N 33/57492 G01N 2333/70596 G01N 33/6872 G01N 33/574 A61K 2039/505

Filing Date

2020-08-28

Application No.

17924941

Claims

20