Patent Application: Fluorescence Imaging for Cancer Margin Detection

ChangeBridge: Patent Apps - Diagnosis & Surgery (A61B)

Published September 23rd, 2024

Detected March 30th, 2026

Summary

The USPTO has published a new patent application (US20260083330A1) detailing a method and system for enhanced fluorescence imaging of tissue and cancer margins. The application, filed on September 23, 2024, describes techniques for analyzing tissue using fluorescent agents and biomolecule autofluorescence to identify diseased tissue.

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What changed

This document is a published patent application from the USPTO, not a regulatory rule or guidance. It describes a novel method for tissue analysis using fluorescence imaging to detect cancer margins. The method involves administering a fluorescent agent, using specific excitation lights to detect both the administered agent's fluorescence and the tissue's autofluorescence, and then processing these signals to create an image that distinguishes between different tissue types, including diseased tissue.

As this is a patent application, it does not impose direct regulatory obligations or compliance deadlines on entities. However, it represents a technological advancement in medical diagnostics that could influence future medical device development and clinical practices. Companies operating in the medical device and pharmaceutical sectors, particularly those involved in cancer diagnostics and surgical tools, should be aware of this patented technology as it may impact their product development and intellectual property strategies.

Source document (simplified)

← USPTO Patent Applications

Method and System for Enhanced Fluorescence Tissue and Cancer Margin Imaging

Application US20260083330A1 Kind: A1 Mar 26, 2026

Inventors

Alan Kersey, Rishikesh Pandey

Abstract

A method of analyzing a tissue is provided that includes: administering a fluorescent agent to a tissue; producing a first excitation light that is configured to produce a fluorescence emission from the fluorescent agent administered to the tissue; producing a second excitation light that is configured to produce an autofluorescence emission from a biomolecule of interest present within the tissue; using a photodetector to detect the fluorescence emissions and produce first signals representative thereof, and produce second signals representative of the autofluorescence emission; producing an image using the first and second signals. The image includes a first, second and third portions representative of tissue types present within the tissue; and analyzing the tissue to identify diseased tissue and to distinguish it from the first and second tissue types.