Patent Application for Patient-Specific Protein Interaction Graph

ChangeBridge: Patent Apps - Health Informatics (G16H)

Published September 25th, 2024

Detected March 26th, 2026

Summary

The USPTO has published a patent application (US20260088144A1) for a patient-specific protein-protein interaction graph system. This technology aims to improve clinical decision-making by analyzing patient mutational data and generating personalized interaction graphs for medical analysis tasks.

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What changed

This document is a patent application, not a regulatory rule or guidance. It describes systems and methods for generating a patient-specific protein-protein interaction (PPI) graph using mutational data and an initial PPI graph. The generated graph is then used with machine learning to perform medical analysis tasks for clinical decision-making.

While not a direct regulatory obligation, this patent application signals potential future technological advancements in healthcare informatics. Companies involved in drug discovery, diagnostics, and health data analytics should be aware of such innovations as they may influence future product development and market trends. No immediate compliance actions are required.

Source document (simplified)

← USPTO Patent Applications

PATIENT-SPECIFIC PROTEIN-PROTEIN INTERACTION GRAPH FOR CLINICAL DECISION MAKING

Application US20260088144A1 Kind: A1 Mar 26, 2026

Inventors

Matthias Siebert, Andrei Puiu, Vivek Singh, Ali Kamen

Abstract

Systems and methods for performing one or more medical analysis tasks are provided. 1) patient data comprising mutational data of a patient and 2) an initial PPI (protein-protein interaction) graph are received. A patient-specific PPI graph for the patient is generated based on the mutational data and the initial PPI graph. One or more medical analysis tasks for the patient are performed using a machine learning based network based on the patient data and the patient-specific PPI graph. Results of the medical analysis task are output.