PATIENT-SPECIFIC PROTEIN-PROTEIN INTERACTION GRAPH FOR CLINICAL DECISION MAKING

Abstract

Systems and methods for performing one or more medical analysis tasks are provided. 1) patient data comprising mutational data of a patient and 2) an initial PPI (protein-protein interaction) graph are received. A patient-specific PPI graph for the patient is generated based on the mutational data and the initial PPI graph. One or more medical analysis tasks for the patient are performed using a machine learning based network based on the patient data and the patient-specific PPI graph. Results of the medical analysis task are output.

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