Monitoring and analysis of invasive and non-invasive electrophysiological signals

ChangeBridge: Patent Grants - Diagnosis & Surgery (A61B)

Published March 31st, 2026

Detected March 31st, 2026

Summary

The USPTO granted Cardioinsight Technologies Inc. Patent US12588850B2 covering a computer-implemented method for monitoring and analyzing electrophysiological signals using both invasive and body surface electrodes. The patent protects technology for reconstructing cardiac electrophysiological signals on surfaces of interest within a patient's body, with geometry data that adapts based on movement of invasive electrodes.

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What changed

Cardioinsight Technologies Inc. obtained US Patent 12588850B2 (Application No. 18827011, granted March 31, 2026) for a method of storing and processing electrophysiological measurement data from invasive and non-invasive electrodes. The patent covers storing location data for movable invasive electrodes, body surface electrode measurements, and three-dimensional geometry data representing patient anatomy and electrode positions, enabling reconstruction of electrophysiological signals on surfaces of interest.

Medical device companies developing cardiac monitoring or electrophysiology equipment should review this patent to assess potential licensing needs or design-around opportunities. Healthcare institutions implementing invasive cardiac mapping should ensure any related technology procurement accounts for intellectual property considerations. This patent does not impose compliance obligations but establishes enforceable intellectual property rights in the cardiac signal monitoring domain.

Source document (simplified)

← USPTO Patent Grants

Monitoring and analysis of invasive and non-invasive electrophysiological signals

Grant US12588850B2 Kind: B2 Mar 31, 2026

Assignee

CARDIOINSIGHT TECHNOLOGIES INC

Inventors

Timothy G. Laske, Qingguo Zeng, Qing Lou

Abstract

A computer-implemented method includes storing location data for at least one invasive electrode that is movable within a patient's body. The method also includes storing electrophysiological measurement data representing the electrophysiological signals measured at the outer surface of a patient's body by body surface electrodes and within the patient's body by the at least one invasive electrode. The method also includes storing geometry data representing anatomy of the patient spatially, and locations of the respective body surface electrodes and the at least one invasive electrode in three-dimensional space. The geometry data for the at least one invasive electrode can vary based on movement of the at least one invasive electrode within the patient's body. The method also includes reconstructing electrophysiological signals on a surface of interest within the patient's body based on the electrophysiological measurement data and the geometry data.