Pressure Balancing Across Microfluidic Devices
Summary
USPTO published patent application US20260097163A1 by Astrin Biosciences, Inc. The application covers an aphaeretic biopsy system using microfluidic devices with inertial separation techniques to extract released tumor cells from patient bloodstream. The system includes a removable cartridge with stacked microfluidic devices implementing pressure balancing to distribute blood evenly across devices for improved separation performance.
What changed
USPTO published patent application US20260097163A1 for Astrin Biosciences, Inc. covering an aphaeretic biopsy system that uses a removable cartridge with stacked microfluidic devices to separate released tumor cells from patient bloodstream via inertial separation techniques. The system implements pressure balancing across multiple devices for even blood distribution and improved separation performance.
The published application establishes priority rights for the assignee and provides technical disclosure of the invention. Competitors developing similar microfluidic cell separation technology should review for potential infringement concerns and freedom-to-operate analysis.
What to do next
- Monitor for patent issuance
Archived snapshot
Apr 13, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
PRESSURE BALANCING ACROSS MICROFLUIDIC DEVICES
Application US20260097163A1 Kind: A1 Apr 09, 2026
Assignee
Astrin Biosciences, Inc.
Inventors
Mahdi Ahmadi, Kaylee Judith Kamalanathan, Jiarong Hong, Jayant Parthasarathy
Abstract
The present aspects relate to an aphaeretic biopsy system. The aphaeretic biopsy system can implement a dialysis process to obtain a bloodstream by a draw line, separate released tumor cells (RTCs) from the bloodstream, capture the RTCs in a reservoir for further analysis, and return the remaining portion of the bloodstream to the patient via a return line. The system can include a removable cartridge that comprises a stack of microfluidic devices configured to implement inertial separation techniques to separate the RTCs from the bloodstream. The stack of microfluidic devices can implement pressure balancing techniques to balance a pressure across multiple devices. The pressure balancing can allow for an even distribution of blood across multiple microfluidic devices and increased performance in separating RTCs from the bloodstream.
CPC Classifications
A61M 1/38 A61B 10/02 A61M 1/36225 A61M 2205/3337
Filing Date
2023-09-22
Application No.
19113966
Named provisions
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